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Study · Not a test of the peptide alone · 1982

2 results

New insight into lymphocytic chalone research. The 'facteur thymique Sérique' might be responsible for part of the immunosuppressive activity detected in the 'chalone fraction'.

Lenfant M, Millerioux L

International archives of allergy and applied immunology1 Jan 1982Cited by 2 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Thymulin (serum thymic factor) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymulin (serum thymic factor).

  1. 01AnimalNot a test of Thymulin (serum thymic factor) aloneAnimal study (in vivo)Activity measurement

    In mice, a purified bovine splenic peptide with properties identical to FTS showed immunosuppressive activity in a T-cell-dependent humoral response assay.

    In plain wordsIn mice, a bovine spleen peptide with properties identical to FTS suppressed a T-cell-dependent immune response.

    Outcome
    DecreaseT-cell-dependent humoral response suppression
    Study

    mousen: not reported in source

    T-cell-dependent humoral response assay
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Following the immunosuppression of a T cell-dependent humoral response in mice as assay, we purified a peptide to homogeneity present at a concentration of 10-50 ng/kg of spleen whose properties were identical to those of the serum thymic factor.
    1 context sentence
    Summary · context
    Immunosuppressive activities have been detected in bovine spleen extracts and attributed to the presence of a 'lymphocytic chalone'.

    In this study, Thymulin (serum thymic factor) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymulin (serum thymic factor).

  2. 02LabNot a test of Thymulin (serum thymic factor) aloneIn vitro (cell-free)Activity measurement

    In bovine spleen extracts, a purified peptide with properties identical to FTS occurred at 10-50 ng/kg of spleen.

    In plain wordsIn lab tests, bovine spleen contained a peptide with properties identical to FTS.

    Outcome
    Not applicableConcentration and FTS-like identity of splenic peptide
    Study

    bovinen: not reported in source

    Purified spleen extract
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Measurements

    Peptide concentration
    10 to 50 ng/kg
    bovine spleen

    Source sentences

    Summary
    Following the immunosuppression of a T cell-dependent humoral response in mice as assay, we purified a peptide to homogeneity present at a concentration of 10-50 ng/kg of spleen whose properties were identical to those of the serum thymic factor.
    1 context sentence
    Summary · context
    Immunosuppressive activities have been detected in bovine spleen extracts and attributed to the presence of a 'lymphocytic chalone'.

    In this study, Thymulin (serum thymic factor) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymulin (serum thymic factor).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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