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Study · Case report or series · n = 1 · 1984

3 results

Sleep disturbances in a case of brain-stem lesions; pharmacological study.

Laffont F, Cathala HP, Ernst A, Bormer M, Schneider-Helmert D, Schoenenberger GA

Electroencephalography and clinical neurophysiology1 Jan 1984Cited by 2 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanCase report or seriesEfficacy outcome

    In a patient with severe insomnia after brain-stem lesions, slow injection of DSIP improved sleep both quantitatively and qualitatively.

    In plain wordsIn one patient with insomnia after brain-stem lesions, DSIP injection improved both how much and how well he or she slept.

    Outcome
    IncreaseSleep quantity and quality
    Study

    n = 1

    Outcome group
    Sleep · Sleep
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Slow injection of delta-sleep-inducing peptide (DSIP) improved sleep both quantitatively and qualitatively
    1 context sentence
    Summary · context
    A pharmacological study was carried out of a case of severe insomnia following brain-stem lesions; several polygraphic controls were used.
  2. 02HumanCase report or seriesEfficacy outcome

    In a patient with severe insomnia after brain-stem lesions, paradoxical sleep latency remained short after DSIP.

    In plain wordsIn one patient with insomnia, the time to reach paradoxical sleep stayed short after DSIP.

    Outcome
    No significant changeParadoxical sleep latency
    Study

    n = 1

    Outcome group
    Sleep · Sleep
    Studied dose
    Dose not stated

    Source sentences

    Summary
    although PS latency remained short.
    1 context sentence
    Summary · context
    A pharmacological study was carried out of a case of severe insomnia following brain-stem lesions; several polygraphic controls were used.
  3. 03HumanCase report or seriesEfficacy outcome

    In a patient with severe insomnia after brain-stem lesions, the effects of DSIP on sleep were reversible.

    In plain wordsIn one patient with insomnia, the sleep effects of DSIP went away again.

    Outcome
    Not applicableReversibility of DSIP effects on sleep
    Study

    n = 1

    Outcome group
    Sleep · Sleep
    Studied dose
    Dose not stated

    Source sentences

    Summary
    These effects were reversible.
    1 context sentence
    Summary · context
    A pharmacological study was carried out of a case of severe insomnia following brain-stem lesions; several polygraphic controls were used.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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