Skip to content

Study · Measured the body's own peptide · 1983

3 results

Distribution of bombesin, somatostatin, substance-P and vasoactive intestinal polypeptide in feline and porcine skin.

O'Shaughnessy DJ, McGregor GP, Ghatei MA, Blank MA, Springall DR, Gu J, Polak JM, Bloom SR

Life sciences1 Jun 1983Cited by 32 (Europe PMC)

PMID6190065 (opens in a new tab)DOI10.1016/0024-3205(83)90318-1 (opens in a new tab)PepBankPUB-06190065
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In cat skin, VIP-immunoreactivity was below the assay detection in the body and highest in the front and rear footpads (17 +/- 7 and 29 +/- 6).

    In plain wordsIn cats, the body's own VIP in skin was undetectable on the body and highest in the footpads.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableVIP-immunoreactivity in cat skin
    Study

    catn: not reported in source

    skin
    Outcome group
    Endogenous peptide levels · Skin and wound

    Measurements

    VIP-IR
    17
    front footpads
    VIP-IR
    29
    rear footpads

    Source sentences

    Summary
    In contrast, vasoactive intestinal polypeptide (VIP)-IR showed greater variability in the cat, being below the assay's detection in the body and highest in the front and rear footpads (17 +/- 7 and 29 +/- 6 respectively
    1 context sentence
    Summary · context
    The content and distribution of several regulatory peptides in the skin of cats and pigs, freshly obtained at surgery, have been investigated.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In pig skin, most regions had low VIP-immunoreactivity, except the snout, which peaked at 12.0 +/- 5.0.

    In plain wordsIn pigs, the body's own VIP in skin was low in most regions, except the snout.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableVIP-immunoreactivity in pig skin
    Study

    pign: not reported in source

    skin
    Outcome group
    Endogenous peptide levels · Skin and wound

    Measurements

    VIP-IR
    12
    snout

    Source sentences

    Summary
    but in the pig most regions exhibited low concentrations with the exception of the snout which peaked at 12.0 +/- 5.0.
    1 context sentence
    Summary · context
    The content and distribution of several regulatory peptides in the skin of cats and pigs, freshly obtained at surgery, have been investigated.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    VIP-immunoreactivity was present in nerve fibres and was concentrated in deeper skin layers, often associated with sweat glands and blood vessels.

    In plain wordsIn cat and pig skin, the body's own VIP sat in nerve fibres, mostly in deeper layers near sweat glands and blood vessels.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableLocalisation of VIP-immunoreactivity in skin
    Study

    cat, pign: not reported in source

    skin
    Outcome group
    Endogenous peptide levels · Skin and wound

    Source sentences

    Summary
    Immunocytochemical localisation showed the peptides to be present in nerve fibres.
    2 context sentences
    Summary · context
    while VIP-IR was more concentrated in deeper layers, often associated with sweat glands and blood vessels.
    Summary · context
    The content and distribution of several regulatory peptides in the skin of cats and pigs, freshly obtained at surgery, have been investigated.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.