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Study · Animal study (in vivo) · rat · 1980

3 results

[Protein and RNA concentration in the supraoptic nucleus of the rat brain during sleep induced by delta-hypnogenic peptide].

Demin NN, Karmanova IG, Maksimuk VF, Rubinskaia NL

Zhurnal evoliutsionnoi biokhimii i fiziologii1 May 1980Cited by 1 (Europe PMC)

PMID6157271 (opens in a new tab)PepBankPUB-06157271
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rats, sleep induced by DSIP was not accompanied by accumulation of proteins in the glia of the supraoptic nucleus, unlike natural sleep.

    In plain wordsIn rats, DSIP-induced sleep did not raise protein in brain support cells the way natural sleep does.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeProtein concentration in supraoptic nuclear glia
    Study

    ratn: not reported in source

    Comparator
    Natural sleep
    Outcome group
    Sleep · Nervous system and cognition
    Studied dose
    Dose not stated · suboccipital injectionAs given in this study (rat).

    Source sentences

    Summary
    It has been shown that specific sleep induced by suboccipital injection of a synthetic delta-hypnogen peptide (delta-sleep inducing peptide, according to M. Monnier) is not accompanied in rats by accumulation of proteins and RNA in the supraoptic nuclear glia--the anabolic process characteristic for natural sleep.
    1 context sentence
    Title · context
    [Protein and RNA concentration in the supraoptic nucleus of the rat brain during sleep induced by delta-hypnogenic peptide].
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rats, sleep induced by DSIP was not accompanied by accumulation of RNA in the glia of the supraoptic nucleus, unlike natural sleep.

    In plain wordsIn rats, DSIP-induced sleep did not raise RNA in brain support cells the way natural sleep does.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeRNA concentration in supraoptic nuclear glia
    Study

    ratn: not reported in source

    Comparator
    Natural sleep
    Outcome group
    Sleep · Nervous system and cognition
    Studied dose
    Dose not stated · suboccipital injectionAs given in this study (rat).

    Source sentences

    Summary
    It has been shown that specific sleep induced by suboccipital injection of a synthetic delta-hypnogen peptide (delta-sleep inducing peptide, according to M. Monnier) is not accompanied in rats by accumulation of proteins and RNA in the supraoptic nuclear glia--the anabolic process characteristic for natural sleep.
    1 context sentence
    Title · context
    [Protein and RNA concentration in the supraoptic nucleus of the rat brain during sleep induced by delta-hypnogenic peptide].
  3. 03AnimalAnimal study (in vivo)Mechanism

    In rats, protein concentration in the cytoplasm of supraoptic neurones increased during DSIP-induced sleep because the cytoplasmic volume fell.

    In plain wordsIn rats, protein concentration in brain nerve cells rose during DSIP-induced sleep, which does not happen in natural sleep.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseProtein concentration in cytoplasm of supraoptic neurones
    Study

    ratn: not reported in source

    Comparator
    Natural sleep
    Outcome group
    Sleep · Nervous system and cognition
    Studied dose
    Dose not stated · suboccipital injectionAs given in this study (rat).

    Source sentences

    Summary
    At the same time, during this artificial sleep protein concentration in the cytoplasm of the neurones in this nucleus increased due to the corresponding reduction of cytoplasmic volume which is absent during natural sleep.
    1 context sentence
    Title · context
    [Protein and RNA concentration in the supraoptic nucleus of the rat brain during sleep induced by delta-hypnogenic peptide].

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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