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Study · Not a test of the peptide alone · 1983

1 result

Aluminium increases permeability of the blood-brain barrier to labelled DSIP and beta-endorphin: possible implications for senile and dialysis dementia.

Banks WA, Kastin AJ

Lancet (London, England)1 Nov 1983Cited by 68 (Europe PMC)

PMID6139573 (opens in a new tab)DOI10.1016/s0140-6736(83)91273-4 (opens in a new tab)PepBankPUB-06139573
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Delta sleep-inducing peptide (DSIP).

  1. 01AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Mechanism

    In rats, intraperitoneal aluminium chloride increased blood-brain barrier permeability to iodinated DSIP by 60-70%.

    In plain wordsIn rats, aluminium injected into the abdomen made the blood-brain barrier more open to labelled DSIP.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseBlood-brain barrier permeability to iodinated DSIP
    Study

    ratn: not reported in source

    rat in vivo
    Outcome group
    Neuroprotection · Nervous system and cognition

    Measurements

    Increase in BBB permeability
    60 to 70%
    iodinated N-Tyr-DSIP after aluminium chloride

    Source sentences

    Summary
    Intraperitoneal injection of aluminium chloride increased the permeability of the BBB to iodinated N-Tyr-delta-sleep-inducing peptide and beta-endorphin by 60-70%.
    1 context sentence
    Summary · context
    The present study shows that aluminium itself affects the permeability of the BBB of rats to small peptides.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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