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Study · Animal study (in vivo) · mouse · 1981

1 result

Neurotensin-induced antinociception in mice: antagonism by thyrotropin-releasing hormone.

Osbahr AJ 3rd, Nemeroff CB, Luttinger D, Mason GA, Prange AJ Jr

The Journal of pharmacology and experimental therapeutics1 Jun 1981Cited by 76 (Europe PMC)

PMID6112261 (opens in a new tab)DOI10.1016/s0022-3565(25)32585-1 (opens in a new tab)PepBankPUB-06112261
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mice, melanostatin did not alter neurotensin-induced antinociception.

    In plain wordsIn mice, melanostatin did not change neurotensin-induced pain relief.

    Peptide
    MIF-1 (Pro-Leu-Gly-NH2)
    Outcome
    No significant changeNeurotensin-induced antinociception
    Study

    mousen: not reported in source

    Neurotensin-induced antinociception
    Outcome group
    Pain · Nervous system and cognition
    Studied dose
    Equimolar dosesAs given in this study (mouse).

    Source sentences

    Summary
    Equimolar doses of another tripeptide (Pro-Leu-Gly-NH2; melanostatin) did not alter the effects of NT.
    1 context sentence
    Summary · context
    Neurotensin (NT), administered intracisternally to mice, produced significant dose-dependent antinociception in three analgesic tests: tail immersion, hot-plate and acetic acid writhing.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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