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Study · Ex vivo tissue · rat · 1984

2 results

Novel ligand specificity of pituitary vasopressin receptors in the rat.

Antoni FA

Neuroendocrinology1 Aug 1984Cited by 98 (Europe PMC)

PMID6089020 (opens in a new tab)DOI10.1159/000123976 (opens in a new tab)PepBankPUB-06089020
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In rat liver membranes, oxytocin had low affinity (KI greater than 10 nM) for vasopressin binding sites.

    In plain wordsIn lab tests with rat liver membranes, oxytocin bound only weakly to vasopressin binding sites.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin affinity for AVP binding sites in liver
    Study

    ratn: not reported in source

    rat liver membrane preparations
    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Measurements

    KI
    > 10 nM
    liver binding sites

    Source sentences

    Summary
    Oxytocin and the antidiuretic (V2) agonist dDAVP had low affinities (KI greater than 10 nM) both for liver and pituitary binding sites.
    1 context sentence
    Summary · context
    The ligand specificities of sites binding tritium-labeled arginine vasopressin (3H-AVP) were investigated in membrane preparations of rat anterior pituitary gland and liver.
  2. 02LabEx vivo tissueActivity measurement

    In rat anterior pituitary membranes, oxytocin had low affinity (KI greater than 10 nM) for vasopressin binding sites.

    In plain wordsIn lab tests with rat anterior pituitary membranes, oxytocin bound only weakly to vasopressin binding sites.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin affinity for AVP binding sites in anterior pituitary
    Study

    ratn: not reported in source

    rat anterior pituitary membrane preparations
    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Measurements

    KI
    > 10 nM
    anterior pituitary binding sites

    Source sentences

    Summary
    Oxytocin and the antidiuretic (V2) agonist dDAVP had low affinities (KI greater than 10 nM) both for liver and pituitary binding sites.
    1 context sentence
    Summary · context
    The ligand specificities of sites binding tritium-labeled arginine vasopressin (3H-AVP) were investigated in membrane preparations of rat anterior pituitary gland and liver.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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