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Study · Animal study (in vivo) · rat · 1985

2 results

Effects of cholecystokinin and vasoactive intestinal peptide on locomotion and rearing in neofrontal decorticated rats.

Katsuura G, Itoh S

Progress in clinical and biological research1 Jan 1985Cited by 2 (Europe PMC)

PMID4080707 (opens in a new tab)PepBankPUB-04080707
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In sham-operated and neofrontal decorticated rats, VIP antagonized the effects of CCK-8 on spontaneous motility, more clearly in decorticated rats.

    In plain wordsIn rats, VIP counteracted the effects of CCK-8 on spontaneous movement, and this was clearer in rats with brain cortex removed.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Direction not reportedSpontaneous motility against CCK-8 effects
    Study

    ratn: not reported in source

    Sham-operated and neofrontal decorticated rats
    Comparator
    CCK-8
    Outcome group
    Exercise and physical function · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The results indicate that VIP antagonizes the effects of CCK-8 on spontaneous motility and rearing, and the effects are more apparent in the decorticated rats.
    1 context sentence
    Summary · context
    In the present investigation the effects of CCK-8 and VIP on spontaneous motility and rearing activity were observed in sham-operated and neofrontal decorticated rats.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In sham-operated and neofrontal decorticated rats, VIP antagonized the effects of CCK-8 on rearing, more clearly in decorticated rats.

    In plain wordsIn rats, VIP counteracted the effects of CCK-8 on rearing, and this was clearer in rats with brain cortex removed.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Direction not reportedRearing activity against CCK-8 effects
    Study

    ratn: not reported in source

    Sham-operated and neofrontal decorticated rats
    Comparator
    CCK-8
    Outcome group
    Exercise and physical function · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The results indicate that VIP antagonizes the effects of CCK-8 on spontaneous motility and rearing, and the effects are more apparent in the decorticated rats.
    1 context sentence
    Summary · context
    In the present investigation the effects of CCK-8 and VIP on spontaneous motility and rearing activity were observed in sham-operated and neofrontal decorticated rats.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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