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Study · In vitro (cell-free) · rat · 1985

2 results

[The effect and changes in oxygen consumption of rat brain homogenates: in vitro effect of a peptide derivative].

Windisch M, Piswanger A

Arzneimittel-Forschung1 Jan 1985

PMID4074439 (opens in a new tab)PepBankPUB-04074439
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cell-free)Activity measurement

    In rat brain homogenates, in vitro cerebrolysin significantly stimulated respiration in all age groups.

    In plain wordsIn lab tests, cerebrolysin increased respiration in brain homogenates from rats of all tested ages.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseBrain homogenate respiration
    Study

    ratn: not reported in source

    Rat brain homogenates
    Outcome group
    Mitochondrial function · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In vitro application of the peptide derivative stimulates respiration significantly in all groups.
    1 context sentence
    Summary · context
    The effect of a peptide derivative (Cerebrolysin) on oxygen consumption of brain homogenates was investigated in 1-day-old, 1-, 2-, 3- and 4-week-old and 2-, 4-, 8-, 12- and 18-month-old rats.
  2. 02LabIn vitro (cell-free)Activity measurement

    In rat brain homogenates, cerebrolysin produced maximal relative respiration increases in very young and older animals.

    In plain wordsIn lab tests, cerebrolysin increased rat brain homogenate respiration most in very young and older groups compared with other ages.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseAge-related relative respiration stimulation
    Study

    ratn: not reported in source

    Rat brain homogenates
    Comparator
    Other tested age groups
    Outcome group
    Mitochondrial function · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    There is striking evidence for a maximal relative increase in extremely young animals up to 2 weeks of life and in rather old ones aged 12 and 18 months.
    1 context sentence
    Summary · context
    The effect of a peptide derivative (Cerebrolysin) on oxygen consumption of brain homogenates was investigated in 1-day-old, 1-, 2-, 3- and 4-week-old and 2-, 4-, 8-, 12- and 18-month-old rats.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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