Skip to content

Study · Animal study (in vivo) · rat · 1985

3 results

Oxytocin stimulates lordosis behavior in female rats.

Arletti R, Bertolini A

Neuropeptides1 Jun 1985Cited by 132 (Europe PMC)

PMID4022280 (opens in a new tab)DOI10.1016/0143-4179(85)90095-2 (opens in a new tab)PepBankPUB-04022280
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In ovariectomized, estrogen and progesterone treated female rats, intraperitoneal oxytocin significantly increased the lordosis response to a mounting male.

    In plain wordsIn female rats, oxytocin injected into the abdomen increased mating-posture response to a male.

    Peptide
    Oxytocin
    Outcome
    IncreaseLordosis response
    Study

    ratn: not reported in source

    ovariectomized, estrogen/progesterone treated female rats
    Comparator
    Saline
    Outcome group
    Sexual function · Reproductive and sexual health
    Studied dose
    200 ng/rat · intraperitonealAs given in this study (rat).

    Measurements

    dose
    200 ng/rat
    intraperitoneal

    Source sentences

    Summary
    Oxytocin, either intraperitoneally injected (200 ng/rat) or intracerebroventricularly infused (1 ng/rat in 4 microliters saline) 60 and 15 min respectively before testing, significantly increased the lordosis response to the mounting male of ovariectomized, estrogen/progesterone treated rats.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In ovariectomized, estrogen and progesterone treated female rats, intracerebroventricular oxytocin significantly increased the lordosis response to a mounting male.

    In plain wordsIn female rats, oxytocin infused into the brain ventricles increased mating-posture response to a male.

    Peptide
    Oxytocin
    Outcome
    IncreaseLordosis response
    Study

    ratn: not reported in source

    ovariectomized, estrogen/progesterone treated female rats
    Comparator
    Saline
    Outcome group
    Sexual function · Reproductive and sexual health
    Studied dose
    1 ng/rat · intracerebroventricularAs given in this study (rat).

    Measurements

    dose
    1 ng/rat
    intracerebroventricular

    Source sentences

    Summary
    Oxytocin, either intraperitoneally injected (200 ng/rat) or intracerebroventricularly infused (1 ng/rat in 4 microliters saline) 60 and 15 min respectively before testing, significantly increased the lordosis response to the mounting male of ovariectomized, estrogen/progesterone treated rats.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In female rats, intracerebroventricular oxytocin at 0.1 ng/rat had no effect on lordosis.

    In plain wordsIn female rats, a lower dose of oxytocin infused into the brain ventricles had no effect on mating-posture response.

    Peptide
    Oxytocin
    Outcome
    No significant changeLordosis response
    Study

    ratn: not reported in source

    ovariectomized, estrogen/progesterone treated female rats
    Comparator
    Saline
    Outcome group
    Sexual function · Reproductive and sexual health
    Studied dose
    0.1 ng/rat · intracerebroventricularAs given in this study (rat).

    Measurements

    dose
    0.1 ng/rat
    intracerebroventricular

    Source sentences

    Summary
    The intracerebroventricular infusion of oxytocin 0.1 ng/rat had no effect; nor did saline.
    1 context sentence
    Summary · context
    Oxytocin, either intraperitoneally injected (200 ng/rat) or intracerebroventricularly infused (1 ng/rat in 4 microliters saline) 60 and 15 min respectively before testing, significantly increased the lordosis response to the mounting male of ovariectomized, estrogen/progesterone treated rats.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.