Human ovarian oxytocin: its source and relationship to steroid hormones.

Dawood MY, Khan-Dawood FS

American journal of obstetrics and gynecology1 Apr 1986Cited by 29 (Europe PMC)

PMID3963065DOI10.1016/0002-9378(86)90450-3PepBankPUB-03963065

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study13

No result from this study comes from a test of the peptide.

Natural levels measured12

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01HumanEndogenous levelObservational studyOther
In human ovaries, the body's own oxytocin concentration was higher in corpus luteum than in corpus albicans.
In plain wordsIn human ovaries, the body's own oxytocin was higher in the corpus luteum than in corpus albicans.
Peptide
Oxytocin
Outcome
IncreaseOxytocin in corpus luteum versus corpus albicans
Study
n: not reported in source
Comparator
Corpus albicans
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Corpus luteum had significantly higher oxytocin, estrone, estradiol, and progesterone concentrations than corpus albicans and ovarian stroma (p = less than 0.01 to less than 0.001).
1 context sentence(design, population, supporting numbers)
Summary · context
To determine the site of oxytocin in human ovaries and its relationship with ovarian steroids, oxytocin and steroid hormones were measured in ovarian tissues, ovarian vein, and peripheral blood.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0396306501
02HumanEndogenous levelObservational studyOther
In human corpus luteum, the body's own oxytocin concentration correlated significantly with estrone concentration.
In plain wordsIn human ovaries, the body's own oxytocin levels in the corpus luteum were linked to estrone levels.
Peptide
Oxytocin
Outcome
Not applicableCorrelation of corpus luteum oxytocin with estrone
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Oxytocin concentrations in corpus luteum correlated significantly with estrone, estradiol, and progesterone.
1 context sentence(design, population, supporting numbers)
Summary · context
To determine the site of oxytocin in human ovaries and its relationship with ovarian steroids, oxytocin and steroid hormones were measured in ovarian tissues, ovarian vein, and peripheral blood.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0396306502
03HumanEndogenous levelObservational studyOther
In human corpus luteum, the body's own oxytocin concentration was higher in the midluteal than early luteal phase.
In plain wordsIn human ovaries, the body's own oxytocin in the corpus luteum was higher in the midluteal than early luteal phase.
Peptide
Oxytocin
Outcome
IncreaseCorpus luteum oxytocin, early versus midluteal phase
Study
n: not reported in source
Comparator
Early luteal phase
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Measurements
Oxytocin, early luteal phase
14 ng/gm wet weight
corpus luteum
Oxytocin, midluteal phase
30.8 ng/gm wet weight
corpus luteum
Source sentences
Summary
Oxytocin in corpus luteum increased from 14.0 +/- 1.8 ng/gm of wet weight in early to 30.8 +/- 0.9 ng/gm in midluteal phases (p = less than 0.001).
1 context sentence(design, population, supporting numbers)
Summary · context
To determine the site of oxytocin in human ovaries and its relationship with ovarian steroids, oxytocin and steroid hormones were measured in ovarian tissues, ovarian vein, and peripheral blood.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0396306503
04HumanEndogenous levelObservational studyOther
Plasma oxytocin of the body's own origin was higher in the ovarian vein draining the corpus luteum than in the ovarian vein without corpus luteum.
In plain wordsThe body's own oxytocin in blood was higher in the ovarian vein that drains the corpus luteum than in a vein without one.
Peptide
Oxytocin
Outcome
IncreasePlasma oxytocin in ovarian vein draining corpus luteum versus vein without corpus luteum
Study
n: not reported in source
Comparator
Ovarian vein without corpus luteum
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Measurements
Plasma oxytocin
11.8 pg/ml
ovarian vein draining corpus luteum
Plasma oxytocin
2.1 pg/ml
ovarian vein without corpus luteum
Source sentences
Summary
Ovarian vein draining corpus luteum had significantly higher plasma oxytocin (11.8 +/- 1.5 pg/ml) than those without corpus luteum (2.1 +/- 0.2 pg/ml) or in the peripheral blood (2.9 +/- 0.3 pg/ml) (p = less than 0.001).
1 context sentence(design, population, supporting numbers)
Summary · context
To determine the site of oxytocin in human ovaries and its relationship with ovarian steroids, oxytocin and steroid hormones were measured in ovarian tissues, ovarian vein, and peripheral blood.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0396306504
05HumanEndogenous levelObservational studyOther
Plasma oxytocin of the body's own origin was higher in the ovarian vein draining the corpus luteum than in peripheral blood.
In plain wordsThe body's own oxytocin in blood was higher in the ovarian vein that drains the corpus luteum than in peripheral blood.
Peptide
Oxytocin
Outcome
IncreasePlasma oxytocin in ovarian vein draining corpus luteum versus peripheral blood
Study
n: not reported in source
Comparator
Peripheral blood
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Measurements
Plasma oxytocin
11.8 pg/ml
ovarian vein draining corpus luteum
Plasma oxytocin
2.9 pg/ml
peripheral blood
Source sentences
Summary
Ovarian vein draining corpus luteum had significantly higher plasma oxytocin (11.8 +/- 1.5 pg/ml) than those without corpus luteum (2.1 +/- 0.2 pg/ml) or in the peripheral blood (2.9 +/- 0.3 pg/ml) (p = less than 0.001).
1 context sentence(design, population, supporting numbers)
Summary · context
To determine the site of oxytocin in human ovaries and its relationship with ovarian steroids, oxytocin and steroid hormones were measured in ovarian tissues, ovarian vein, and peripheral blood.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0396306505
06HumanEndogenous levelObservational studyOther
In human corpus luteum, the body's own oxytocin concentration correlated significantly with its ipsilateral ovarian vein oxytocin level.
In plain wordsIn human ovaries, the body's own oxytocin in the corpus luteum was linked to oxytocin levels in the nearby ovarian vein.
Peptide
Oxytocin
Outcome
Not applicableCorrelation of corpus luteum oxytocin with ipsilateral ovarian vein oxytocin
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Oxytocin in corpus luteum correlated significantly with its ipsilateral ovarian vein level of oxytocin, estrone, progesterone, and 17 alpha-hydroxyprogesterone.
1 context sentence(design, population, supporting numbers)
Summary · context
To determine the site of oxytocin in human ovaries and its relationship with ovarian steroids, oxytocin and steroid hormones were measured in ovarian tissues, ovarian vein, and peripheral blood.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0396306506
07HumanEndogenous levelObservational studyOther
In human ovaries, the body's own oxytocin concentration was higher in corpus luteum than in ovarian stroma.
In plain wordsIn human ovaries, the body's own oxytocin was higher in the corpus luteum than in ovarian stroma.
Peptide
Oxytocin
Outcome
IncreaseOxytocin in corpus luteum versus ovarian stroma
Study
n: not reported in source
Comparator
Ovarian stroma
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Corpus luteum had significantly higher oxytocin, estrone, estradiol, and progesterone concentrations than corpus albicans and ovarian stroma (p = less than 0.01 to less than 0.001).
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0396306508
08HumanEndogenous levelObservational studyOther
In human corpus luteum, the body's own oxytocin concentration correlated significantly with estradiol concentration.
In plain wordsIn human ovaries, the body's own oxytocin levels in the corpus luteum were linked to estradiol levels.
Peptide
Oxytocin
Outcome
Not applicableCorrelation of corpus luteum oxytocin with estradiol
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Oxytocin concentrations in corpus luteum correlated significantly with estrone, estradiol, and progesterone.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0396306509
09HumanEndogenous levelObservational studyOther
In human corpus luteum, the body's own oxytocin concentration correlated significantly with progesterone concentration.
In plain wordsIn human ovaries, the body's own oxytocin levels in the corpus luteum were linked to progesterone levels.
Peptide
Oxytocin
Outcome
Not applicableCorrelation of corpus luteum oxytocin with progesterone
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Oxytocin concentrations in corpus luteum correlated significantly with estrone, estradiol, and progesterone.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0396306510
10HumanEndogenous levelObservational studyOther
In human corpus luteum, the body's own oxytocin concentration correlated significantly with ipsilateral ovarian vein estrone level.
In plain wordsIn human ovaries, the body's own oxytocin in the corpus luteum was linked to estrone levels in the nearby ovarian vein.
Peptide
Oxytocin
Outcome
Not applicableCorrelation of corpus luteum oxytocin with ipsilateral ovarian vein estrone
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Oxytocin in corpus luteum correlated significantly with its ipsilateral ovarian vein level of oxytocin, estrone, progesterone, and 17 alpha-hydroxyprogesterone.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0396306511
11HumanEndogenous levelObservational studyOther
In human corpus luteum, the body's own oxytocin concentration correlated significantly with ipsilateral ovarian vein progesterone level.
In plain wordsIn human ovaries, the body's own oxytocin in the corpus luteum was linked to progesterone levels in the nearby ovarian vein.
Peptide
Oxytocin
Outcome
Not applicableCorrelation of corpus luteum oxytocin with ipsilateral ovarian vein progesterone
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Oxytocin in corpus luteum correlated significantly with its ipsilateral ovarian vein level of oxytocin, estrone, progesterone, and 17 alpha-hydroxyprogesterone.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0396306512
12HumanEndogenous levelObservational studyOther
In human corpus luteum, the body's own oxytocin concentration correlated significantly with ipsilateral ovarian vein 17 alpha-hydroxyprogesterone level.
In plain wordsIn human ovaries, the body's own oxytocin in the corpus luteum was linked to 17 alpha-hydroxyprogesterone levels in the nearby ovarian vein.
Peptide
Oxytocin
Outcome
Not applicableCorrelation of corpus luteum oxytocin with ipsilateral ovarian vein 17 alpha-hydroxyprogesterone
Study
n: not reported in source
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Oxytocin in corpus luteum correlated significantly with its ipsilateral ovarian vein level of oxytocin, estrone, progesterone, and 17 alpha-hydroxyprogesterone.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0396306513

Studies that did not test the peptide alone1

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

13LabNot a test of Oxytocin aloneIn vitro (cell-free)Other
Reverse phase HPLC showed that oxytocin extracted from human corpus luteum was similar to synthetic oxytocin.
In plain wordsIn a laboratory chemical test, oxytocin extracted from human corpus luteum was similar to synthetic oxytocin.
Peptide
Oxytocin
Outcome
Not applicableHPLC comparison of corpus luteum oxytocin with synthetic oxytocin
Study
humann: not reported in source
Oxytocin extracted from human corpus luteum
Comparator
Synthetic oxytocin
Outcome group
Peptide structure and chemistry · Reproductive and sexual health
Source sentences
Summary
Reverse phase high pressure liquid chromatography showed similarity between oxytocin in corpus luteum and synthetic oxytocin.
1 context sentence(design, population, supporting numbers)
Summary · context
To determine the site of oxytocin in human ovaries and its relationship with ovarian steroids, oxytocin and steroid hormones were measured in ovarian tissues, ovarian vein, and peripheral blood.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-0396306507

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
11 Oct 2026, 20:03 UTC
Study results updated
Version 1
9 Oct 2026, 02:52 UTC
First added · source update from Europe PMC

Subjects

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MeSH terms

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