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Study · Measured the body's own peptide · 1985

2 results

Activation of vasopressin neurons in the human supraoptic and paraventricular nucleus in senescence and senile dementia.

Hoogendijk JE, Fliers E, Swaab DF, Verwer RW

Journal of the neurological sciences1 Jul 1985Cited by 59 (Europe PMC)

PMID3897463 (opens in a new tab)DOI10.1016/0022-510x(85)90141-8 (opens in a new tab)PepBankPUB-03897463
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In human supraoptic and paraventricular nuclei, nucleolar size correlated strongly with cell size in oxytocin neurons.

    In plain wordsIn human brain tissue, the nucleolus size of the body's own oxytocin cells was linked to cell size.

    Peptide
    Oxytocin
    Outcome
    Not applicableCorrelation of nucleolar size with cell size in OXT neurons
    Study

    n: not reported in source

    Outcome group
    Aging markers · Aging and longevity

    Source sentences

    Summary
    A strong correlation was found between nucleolar size and cell size, both in AVP and OXT neurons.
    1 context sentence
    Summary · context
    In the present study, the same brain material was used for the determination of nucleolar size in immunocytochemically identified AVP and oxytocin (OXT) neurons as an additional parameter for peptide production.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In human supraoptic and paraventricular nuclei, nucleolar size of oxytocin neurons did not increase significantly in senescence.

    In plain wordsIn human brain tissue, the body's own oxytocin cells did not show larger nucleoli in old age, unlike vasopressin cells.

    Peptide
    Oxytocin
    Outcome
    No significant changeNucleolar size of OXT neurons in senescence
    Study

    n: not reported in source

    Comparator
    Younger adults
    Outcome group
    Aging markers · Aging and longevity

    Source sentences

    Summary
    Nucleolar size of AVP but not of OXT neurons increased significantly in senescence.
    1 context sentence
    Summary · context
    In the present study, the same brain material was used for the determination of nucleolar size in immunocytochemically identified AVP and oxytocin (OXT) neurons as an additional parameter for peptide production.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:54 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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