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Study · Measured the body's own peptide · 1985

2 results

Thymic functions in uremic rats: evidence for thymosin alpha 1 deficiency.

Dosa S, Phillips TM, Abraham A, Kramer NC, McLure JE, Malony PJ, Thompson AM

Nephron1 Jan 1985Cited by 2 (Europe PMC)

PMID3885064 (opens in a new tab)DOI10.1159/000183407 (opens in a new tab)PepBankPUB-03885064
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In rats with chronic renal insufficiency, the body's own intrathymic thymosin alpha‑1 concentration was significantly reduced compared with controls.

    In plain wordsIn rats with kidney failure, the body's own thymosin alpha‑1 in the thymus was lower than in healthy rats.

    Peptide
    Thymosin alpha-1
    Outcome
    DecreaseIntrathymic thymosin alpha 1 concentration in uremic rats
    Study

    ratn: not reported in source

    rats with experimental chronic renal insufficiency
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Quantitative microfluorometry revealed a significant reduction in the intrathymic concentration of a potent immunomodulator, thymosin alpha 1 in all uremic animals.
    1 context sentence
    Summary · context
    Changes in the circulating lymphocyte populations and thymus glands were studied in rats with experimental chronic renal insufficiency (CRI).

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In rats with chronic renal insufficiency, circulating T lymphocyte percentages correlated positively with intrathymic concentrations of the body's own thymosin alpha‑1.

    In plain wordsIn rats with kidney failure, more of the body's own thymosin alpha‑1 in the thymus went with higher T cell percentages in blood.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableCorrelation of circulating T lymphocytes with intrathymic thymosin alpha 1
    Study

    ratn: not reported in source

    rats with experimental chronic renal insufficiency
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    There was a significant positive correlation between the percentages of circulating T lymphocytes and the intrathymic concentrations of thymosin alpha 1.
    1 context sentence
    Summary · context
    Changes in the circulating lymphocyte populations and thymus glands were studied in rats with experimental chronic renal insufficiency (CRI).

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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