In cultured neonatal rabbit osteoclasts, salmon calcitonin inhibited bone resorption at concentrations of 1 pg/ml and above.
In plain wordsIn lab tests, salmon calcitonin at 1 pg/ml and above inhibited bone resorption by neonatal rabbit osteoclasts.
- Peptide
- Calcitonin-salmon
- Outcome
- DecreaseOsteoclastic bone resorption
- Study
rabbitn: not reported in source
Disaggregated neonatal rabbit osteoclasts on devitalized cortical bone- Outcome group
- Bone and joint · Musculoskeletal
- Studied dose
- 1 pg/ml and above · 8 or 24 hAs given in this study (rabbit).
Source sentences
Salmon calcitonin inhibited osteoclastic bone resorption at concentrations of 1 pg/ml and above, while PTH and 1,25-dihydroxyvitamin D3 were without significant effect.
1 context sentence(design, population, supporting numbers)
Osteoclasts were mechanically disaggregated from neonatal rabbit long bones and cultured on slices of devitalized cortical bone for 8 or 24 h.