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Study · Measured the body's own peptide · 1985

3 results

Effect of PGF2 alpha administration on the release of endogenous PGF2 alpha and oxytocin in indomethacin-treated goats.

Homeida AM, Cooke RG

Research in veterinary science1 Jul 1985Cited by 5 (Europe PMC)

PMID3862197 (opens in a new tab)DOI10.1016/s0034-5288(18)31773-9 (opens in a new tab)PepBankPUB-03862197
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In goats in the luteal phase, repeated intramuscular PGF2 alpha injections rapidly increased jugular concentrations of oxytocin.

    In plain wordsIn goats, injections of prostaglandin F2 alpha quickly raised the body's own oxytocin levels in the blood.

    Peptide
    Oxytocin
    Outcome
    IncreaseJugular oxytocin concentration after PGF2 alpha injections
    Study

    goatn: not reported in source

    goats in the luteal phase of the oestrous cycle
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Repeated intramuscular injection of 1 mg prostaglandin F2 alpha (PGF2 alpha) during the luteal phase of the oestrous cycle of the goat hastened luteolysis and resulted in rapid increases in jugular concentrations of 13,14-dihydro-15-keto PGF2 alpha (PGFM), the primary metabolite of PGF2 alpha, and of oxytocin
    1 context sentence
    Title · context
    Effect of PGF2 alpha administration on the release of endogenous PGF2 alpha and oxytocin in indomethacin-treated goats.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In indomethacin-treated goats, PGF2 alpha injections had a reduced effect on oxytocin concentrations.

    In plain wordsIn goats given indomethacin, prostaglandin F2 alpha raised the body's own oxytocin levels less.

    Peptide
    Oxytocin
    Outcome
    DecreaseOxytocin response to PGF2 alpha in indomethacin-treated goats
    Study

    goatn: not reported in source

    goats in the luteal phase of the oestrous cycle
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    similar injections of PGF2 alpha in indomethacin-treated goats had a reduced effect on PGFM and oxytocin concentrations
    1 context sentence
    Title · context
    Effect of PGF2 alpha administration on the release of endogenous PGF2 alpha and oxytocin in indomethacin-treated goats.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In ovariectomised goats, PGF2 alpha injections did not change oxytocin concentrations.

    In plain wordsIn goats with the ovaries removed, prostaglandin F2 alpha did not change the body's own oxytocin levels.

    Peptide
    Oxytocin
    Outcome
    No significant changeOxytocin concentration after PGF2 alpha in ovariectomised goats
    Study

    goatn: not reported in source

    goats in the luteal phase of the oestrous cycle
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    The same injections of PGF2 alpha were without effect on PGFM and oxytocin concentrations in ovariectomised goats.
    1 context sentence
    Title · context
    Effect of PGF2 alpha administration on the release of endogenous PGF2 alpha and oxytocin in indomethacin-treated goats.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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