Splenocytes from thymectomized mice released PGE2 after incubation with thymosin alpha‑1 at 4 micrograms/ml for a short time and at 4-8 micrograms/ml for longer times.
In plain wordsIn lab tests on mouse cells, thymosin alpha‑1 made spleen cells from mice without a thymus release a signalling lipid.
- Peptide
- Thymosin alpha-1
- Outcome
- IncreasePGE2 release by splenocytes from thymectomized mice
- Study
mousen: not reported in source
splenocytes from thymectomized mice- Outcome group
- Immune response · Immune and inflammation
- Studied dose
- 4 micrograms/ml for 15 min; 4-8 micrograms/ml for 60-180 minAs given in this study (mouse).
Source sentences
Splenocytes from Tx mice release PGE2 at short time of incubation (15') using 4 micrograms/ml of Thymosin alpha 1 and at longer time of incubation (60'-180' using 4-8 micrograms/ml of Thymosin alpha 1.
1 context sentence(design, population, supporting numbers)
The effects on PGE2 release by lymphocytes obtained from adult thymectomized mice and from normal mice, after incubation with Thymosin alpha 1, were studied.