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Study · Animal study (in vivo) · mouse · 1985

2 results

Modulation of natural killer activity by thymosin alpha 1 and interferon.

Favalli C, Jezzi T, Mastino A, Rinaldi-Garaci C, Riccardi C, Garaci E

Cancer immunology, immunotherapy : CII1 Jan 1985Cited by 45 (Europe PMC)

PMID3851698 (opens in a new tab)PMCIDPMC11038431 (opens in a new tab)DOI10.1007/bf00205574 (opens in a new tab)PepBankPUB-03851698
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In bone marrow reconstituted murine chimeras, thymosin alpha‑1 accelerated the recovery rate of natural killer cell activity.

    In plain wordsIn mice with reconstituted bone marrow, thymosin alpha‑1 sped up the recovery of natural killer cell activity.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseRecovery rate of NK activity in bone marrow reconstituted chimeras
    Study

    mousen: not reported in source

    murine
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thymosin alpha 1 was, moreover, able to accelerate the recovery rate of NK activity in bone marrow reconstituted murine chimeras.
    1 context sentence
    Summary · context
    A single injection of alpha beta-interferon (alpha beta-IFN) (30000 units/mouse), a major biological modifier of natural killer (NK) cytolytic activity, strongly stimulated NK activity in normal mice, as expected, while the same treatment did not statistically alter the NK response in cyclophosphami…

Studies that did not test the peptide alone1

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

  1. 02AnimalNot a test of Thymosin alpha-1 aloneAnimal study (in vivo)Efficacy outcome

    In cyclophosphamide-suppressed mice, a regimen of thymosin alpha‑1 for 4 days followed by alpha beta-interferon strongly restored natural killer cell activity.

    In plain wordsIn mice with suppressed immunity, thymosin alpha‑1 followed by interferon restored natural killer cell activity.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseNK activity in cyclophosphamide-suppressed mice after thymosin alpha 1 then alpha beta-IFN
    Study

    mousen: not reported in source

    murine
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    The results show that treatment with thymosin alpha 1 (200 micrograms/kg) for 4 days, followed by a single injection of alpha beta-IFN 24 h before testing, strongly restored NK activity in CY-suppressed mice.
    1 context sentence
    Summary · context
    A single injection of alpha beta-interferon (alpha beta-IFN) (30000 units/mouse), a major biological modifier of natural killer (NK) cytolytic activity, strongly stimulated NK activity in normal mice, as expected, while the same treatment did not statistically alter the NK response in cyclophosphami…

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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