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Study · Ex vivo tissue · rat · 1985

1 result

[Effect of leu-enkephalin and the delta-sleep-inducing peptide, M (DSIP), on endogenous noradrenaline release by brain synaptosomes in the rat].

Rozhanets VV, Anosov AK

Biulleten' eksperimental'noi biologii i meditsiny1 Aug 1985

PMID3839701 (opens in a new tab)PepBankPUB-03839701
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueMechanism

    In rat brain synaptosomes, DSIP at concentrations of 10(-8)-10(-5) M did not influence noradrenaline release.

    In plain wordsIn lab tests on rat brain nerve-ending preparations, DSIP did not change noradrenaline release.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeNoradrenaline release from synaptosomes
    Study

    ratn: not reported in source

    Rat brain synaptosomes
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    10(-8)-10(-5) M · 10-minute incubationAs given in this study (rat).

    Source sentences

    Summary
    The delta-sleep-inducing peptide (DSIP) did not influence the neurotransmitter release at concentrations of 10(-8)-10(-5) M.
    2 context sentences
    Summary · context
    Fluorometry was employed to measure the noradrenaline (NA) content in rat brain synaptosomes depending on the duration of incubation, depolarization effects (40 mM KCl or 1.5 mM ouabain), composition of the synaptosomal fraction and concentration of the peptides.
    Summary · context
    The 10-minute incubation in a potassium medium of a suspension of light synaptosomes was used as an optimal test-system for studying the peptide action.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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