In rats with left-ventricular infarction, pretreatment with delta-sleep peptide and its cyclic analogue significantly limited the infarct-related depression of atrial distensibility.
In plain wordsIn rats with induced heart attack, pretreatment with delta-sleep peptide and its cyclic analogue limited the loss of atrial stretchability.
- Outcome
- DecreaseInfarct-related depression of right-atrial distensibility
- Study
ratn: not reported in source
- Outcome group
- Heart function · Cardiovascular
Source sentences
These peptides, administered in a 20 micrograms/kg dose, 1 hour before the induction of experimental infarction, significantly limited the infarct-related depression of atrial distensibility and contractility
1 context sentence(design, population, supporting numbers)
The effect of pretreatment with delta-sleep peptide (DSP) and its cyclic analogue (cDSP) on right-atrial myocardial distensibility and contractility disturbances in left-ventricular infarction (according to Selye) was studied in Wistar rats.
In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).