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Study · Measured the body's own peptide · 1986

4 results

Vasopressin and oxytocin mRNAs in adrenalectomized and Brattleboro rats: analysis by quantitative in situ hybridization histochemistry.

Young WS 3rd, Mezey E, Siegel RE

Brain research1 Dec 1986Cited by 143 (Europe PMC)

PMID3828759 (opens in a new tab)DOI10.1016/0169-328x(86)90029-x (opens in a new tab)PepBankPUB-03828759
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In rat hypothalamus, oxytocin mRNA-containing cells were seen in the paraventricular and supraoptic nuclei.

    In plain wordsIn rats, the body's own oxytocin messenger RNA was found in two hypothalamic regions.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin mRNA in paraventricular and supraoptic nuclei
    Study

    ratn: not reported in source

    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    VP and OT mRNA-containing cells were seen in the paraventricular (PVN) and supraoptic (SON) nuclei.
    1 context sentence
    Summary · context
    35S-labeled synthetic oligodeoxyribonucleotide probes were used to measure levels of vasopressin (VP) and oxytocin (OT) mRNAs in rat hypothalamus by quantitative in situ hybridization histochemistry (ISHH).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In adrenalectomized rats, magnocellular oxytocin mRNA levels did not change.

    In plain wordsIn rats with the adrenal glands removed, the body's own oxytocin messenger RNA did not change.

    Peptide
    Oxytocin
    Outcome
    No significant changeMagnocellular oxytocin mRNA after adrenalectomy
    Study

    ratn: not reported in source

    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    while no changes occurred in magnocellular VP or OT mRNA levels.
    1 context sentence
    Summary · context
    35S-labeled synthetic oligodeoxyribonucleotide probes were used to measure levels of vasopressin (VP) and oxytocin (OT) mRNAs in rat hypothalamus by quantitative in situ hybridization histochemistry (ISHH).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In Brattleboro rats, oxytocin mRNA levels were increased in the magnocellular regions.

    In plain wordsIn Brattleboro rats, the body's own oxytocin messenger RNA was higher in a hypothalamic region.

    Peptide
    Oxytocin
    Outcome
    IncreaseMagnocellular oxytocin mRNA in Brattleboro rats
    Study

    ratn: not reported in source

    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    OT mRNA levels increased in the magnocellular regions.
    1 context sentence
    Summary · context
    35S-labeled synthetic oligodeoxyribonucleotide probes were used to measure levels of vasopressin (VP) and oxytocin (OT) mRNAs in rat hypothalamus by quantitative in situ hybridization histochemistry (ISHH).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Other

    In rat hypothalamus, oxytocin-neurophysin and its encoding mRNA were always located together.

    In plain wordsIn rats, the body's own oxytocin-related protein and its messenger RNA were always found in the same cells.

    Peptide
    Oxytocin
    Outcome
    Not applicableCo-localisation of oxytocin-neurophysin and its mRNA
    Study

    ratn: not reported in source

    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    as were OT-neurophysin and its encoding mRNA.
    1 context sentence
    Summary · context
    35S-labeled synthetic oligodeoxyribonucleotide probes were used to measure levels of vasopressin (VP) and oxytocin (OT) mRNAs in rat hypothalamus by quantitative in situ hybridization histochemistry (ISHH).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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