Skip to content

Study · Animal study (in vivo) · rat · 1986

2 results

Sleep-wave activity of a delta sleep-inducing peptide analog correlates with its penetrance of the blood-brain barrier.

Miller LH, Turnbull BA, Kastin AJ, Coy DH

Sleep1 Jan 1986Cited by 16 (Europe PMC)

PMID3754348 (opens in a new tab)DOI10.1093/sleep/9.1.80 (opens in a new tab)PepBankPUB-03754348
Source linkPubMedAsk about this study
Jump to 2 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats, peripherally injected DSIP significantly increased EEG output in the delta range compared with controls.

    In plain wordsIn rats, DSIP injected into the abdomen increased delta brain-wave activity compared with controls.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseEEG delta wave activity
    Study

    ratn = 10

    Comparator
    Controls
    Outcome group
    Sleep · Sleep
    Studied dose
    Dose not stated · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    DSIP was found to significantly increase EEG output in the delta range when compared with controls.
    1 context sentence
    Summary · context
    Rats (n = 10) were peripherally injected with DSIP and [D-Ala4]DSIP-NH2 during the dark portion of a 12-h light/dark cycle prior to recording of epidural encephalographic (EEG) wave forms.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, DSIP itself had no effect on locomotor activity.

    In plain wordsIn rats, DSIP itself did not change movement activity.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeLocomotor activity
    Study

    ratn = 10

    Comparator
    Controls
    Outcome group
    Sleep · Sleep
    Studied dose
    Dose not stated · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    whereas DSIP itself was without effect.
    1 context sentence
    Summary · context
    Rats (n = 10) were peripherally injected with DSIP and [D-Ala4]DSIP-NH2 during the dark portion of a 12-h light/dark cycle prior to recording of epidural encephalographic (EEG) wave forms.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.