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Study · Measured the body's own peptide · 1986

3 results

Vasopressin and oxytocin in brain areas of rats with high or low behavioral performance.

Ermisch A, Landgraf R, Möbius P

Brain research1 Jul 1986Cited by 13 (Europe PMC)

PMID3742217 (opens in a new tab)DOI10.1016/0006-8993(86)90251-9 (opens in a new tab)PepBankPUB-03742217
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In rats selected for high performance in a foot-shock motivated brightness discrimination task, oxytocin content in the septum/striatum was higher than in low performance rats.

    In plain wordsIn rats, the body's own oxytocin in one brain area was higher in high-performing rats than in low-performing rats.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin content in septum/striatum by performance
    Study

    ratn: not reported in source

    Comparator
    Low performance rats
    Outcome group
    Cognition and memory · Nervous system and cognition

    Source sentences

    Summary
    Compared to the low performance rats, the OXT content of the high performance rats was higher in the septum/striatum
    2 context sentences
    Summary · context
    Animals were selected from a population of 55 rats which differed significantly in their ability to perform a behavioral task, a foot-shock motivated brightness discrimination (BD).
    Summary · context
    Using highly specific and sensitive radioimmunoassays, the contents of arginine vasopressin (AVP) and oxytocin (OXT) were measured in 5 brain areas and the plasma of these animals.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In rats selected for high performance in a foot-shock motivated brightness discrimination task, oxytocin content in the hippocampus was lower than in low performance rats.

    In plain wordsIn rats, the body's own oxytocin in the hippocampus was lower in high-performing rats than in low-performing rats.

    Peptide
    Oxytocin
    Outcome
    DecreaseOxytocin content in hippocampus by performance
    Study

    ratn: not reported in source

    Comparator
    Low performance rats
    Outcome group
    Cognition and memory · Nervous system and cognition

    Source sentences

    Summary
    Compared to the low performance rats, the OXT content of the high performance rats was higher in the septum/striatum, but was lower in the hippocampus.
    2 context sentences
    Summary · context
    Animals were selected from a population of 55 rats which differed significantly in their ability to perform a behavioral task, a foot-shock motivated brightness discrimination (BD).
    Summary · context
    Using highly specific and sensitive radioimmunoassays, the contents of arginine vasopressin (AVP) and oxytocin (OXT) were measured in 5 brain areas and the plasma of these animals.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In rats selected for high or low performance in a brightness discrimination task, oxytocin content did not differ between groups in the hypothalamus, motor cortex or plasma.

    In plain wordsIn rats, the body's own oxytocin in the hypothalamus, motor cortex and blood did not differ between high and low performers.

    Peptide
    Oxytocin
    Outcome
    No significant changeOxytocin content in hypothalamus, motor cortex and plasma by performance
    Study

    ratn: not reported in source

    Comparator
    Low performance rats
    Outcome group
    Cognition and memory · Nervous system and cognition

    Source sentences

    Summary
    No significant differences between the groups were found in the hypothalamus, motor cortex and the plasma.
    2 context sentences
    Summary · context
    Animals were selected from a population of 55 rats which differed significantly in their ability to perform a behavioral task, a foot-shock motivated brightness discrimination (BD).
    Summary · context
    Using highly specific and sensitive radioimmunoassays, the contents of arginine vasopressin (AVP) and oxytocin (OXT) were measured in 5 brain areas and the plasma of these animals.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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