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Study · In vitro (cells) · 1986

2 results

Porphyrin synthesis in primary nervous tissue cultures from 10(-3) M delta-aminolaevulinic acid in the presence of melatonin and neuropeptides.

Durkó I, Juhász A

Neurochemical research1 May 1986Cited by 8 (Europe PMC)

Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In primary glia cell cultures, oxytocin at 10(-5) and 10(-6) M blocked porphyrin synthesis from delta-aminolaevulinic acid; three other neuropeptides were tested in the same series.

    In plain wordsIn cells grown in the lab, oxytocin blocked porphyrin production by glia cells; other neuropeptides were tested in the same series.

    Peptide
    Oxytocin
    Outcome
    DecreasePorphyrin synthesis in glia cells
    Study

    n: not reported in source

    Primary nervous tissue cultures (glia cells, neuronal cells)
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    10(-5) and 10(-6) MAs given in this study.

    Source sentences

    Summary
    Oxytocin, lysine-vasopressin, CCK-8 sulphate ester and des-Tyr-gamma-endorphin in concentrations of 10(-5) and 10(-6) M block the porphyrin synthesis of the glia cells and display different effects on that of the neuronal cells.
  2. 02LabIn vitro (cells)Mechanism

    In primary nervous tissue cultures, oxytocin at 10(-5) and 10(-6) M enhanced total porphyrin synthesis; only 10(-5) M des-Tyr-gamma-endorphin was inhibitory, in glia cells.

    In plain wordsIn cells grown in the lab, oxytocin raised total porphyrin production; other neuropeptides were tested in the same series.

    Peptide
    Oxytocin
    Outcome
    IncreaseTotal porphyrin synthesis of the cell cultures
    Study

    n: not reported in source

    Primary nervous tissue cultures (glia cells, neuronal cells)
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    10(-5) and 10(-6) MAs given in this study.

    Source sentences

    Summary
    Oxytocin, lysine-vasopressin, CCK-8 sulphate ester and des-Tyr-gamma-endorphin in concentrations of 10(-5) and 10(-6) M block the porphyrin synthesis of the glia cells and display different effects on that of the neuronal cells.
    1 context sentence
    Summary · context
    They enhance the total porphyrin synthesis of the cell cultures, with the exception of 10(-5) M des-Tyr-gamma-endorphin, which exerts an inhibitory effect on the glia cells.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:54 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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