In one child, cerebral edema and death attributed to water intoxication followed posterior pituitary injection (an extract with oxytocin and vasopressin) together with a large volume of free water.
In plain wordsIn one child, a pituitary extract injection with a large amount of free water was followed by brain swelling and death.
- Peptide
- Oxytocin
- Outcome
- Not applicableCerebral edema and death with posterior pituitary injection and free water
- Study
n: not reported in source
- Outcome group
- Adverse events · Whole body
Source sentences
We report a case of cerebral edema and death attributed to water intoxication in a child who had received a large volume of free water concurrent with posterior pituitary injection to control bleeding after tonsillectomy and adenoidectomy.
1 context sentence(design, population, supporting numbers)
Posterior pituitary injection is an extract prepared from the dried posterior lobe of the pituitary gland from domestic animals containing two octapeptide hormones, oxytocin and vasopressin.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.