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Study · Animal study (in vivo) · cat and rat · 1987

4 results

[Effect of the delta sleep peptide on epileptic activity in the cerebral cortex of rats and cats].

Kryzhanovskiĭ GN, Shandra AA, Godlevskiĭ LS, Karpova MN, Mikhaleva II

Biulleten' eksperimental'noi biologii i meditsiny1 Nov 1987Cited by 3 (Europe PMC)

PMID3676495 (opens in a new tab)PepBankPUB-03676495
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats, intraperitoneal DSIP suppressed penicillin-induced moderate epileptic foci that generated spike potentials.

    In plain wordsIn rats, DSIP reduced moderate epileptic activity that was induced with penicillin.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreasePenicillin-induced moderate epileptic foci spike potentials
    Study

    ratn: not reported in source

    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    100 micrograms/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    In free behaviour experiments on rats it has been shown that the intraperitoneal injection of delta sleep-inducing peptide (DSIP) (100 micrograms/kg) suppressed penicillin-induced relatively moderate epileptic foci which generated spike potentials as well as severe foci with ictal epileptic discharges.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, intraperitoneal DSIP suppressed severe penicillin-induced foci with ictal epileptic discharges.

    In plain wordsIn rats, DSIP reduced severe epileptic activity that was induced with penicillin.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreasePenicillin-induced severe epileptic foci with ictal discharges
    Study

    ratn: not reported in source

    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    100 micrograms/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    In free behaviour experiments on rats it has been shown that the intraperitoneal injection of delta sleep-inducing peptide (DSIP) (100 micrograms/kg) suppressed penicillin-induced relatively moderate epileptic foci which generated spike potentials as well as severe foci with ictal epileptic discharges.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In cats, intravenous DSIP suppressed a strychnine-induced epileptic focus.

    In plain wordsIn cats, DSIP reduced an epileptic focus that was induced with strychnine.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseStrychnine-induced epileptic focus
    Study

    catn: not reported in source

    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    100 micrograms/kg · intravenousAs given in this study (cat).

    Source sentences

    Summary
    In the experiments on cats it was shown that intravenous DSIP injection (100 micrograms/kg) suppressed strychnine-induced epileptic focus and complexes of epileptic foci.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In cats, intravenous DSIP suppressed strychnine-induced complexes of epileptic foci.

    In plain wordsIn cats, DSIP reduced groups of epileptic foci that were induced with strychnine.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseStrychnine-induced complexes of epileptic foci
    Study

    catn: not reported in source

    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    100 micrograms/kg · intravenousAs given in this study (cat).

    Source sentences

    Summary
    In the experiments on cats it was shown that intravenous DSIP injection (100 micrograms/kg) suppressed strychnine-induced epileptic focus and complexes of epileptic foci.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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