The effect of "facteur thymique serique" (FTS) on catecholamine and serotonin neurotransmission in discrete brain regions of mice.

Vécsei L, Faludi M, Najbauer J

Acta physiologica Hungarica1 Jan 1987Cited by 3 (Europe PMC)

PMID3591350PepBankPUB-03591350

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study10

10 results from studies that gave the peptide. No result from this study comes from people.

01AnimalAnimal study (in vivo)Mechanism
In mice, FTS increased mesencephalic serotonin content.
In plain wordsIn mice, FTS increased serotonin in the midbrain.
Peptide
Thymulin (serum thymic factor)
Outcome
IncreaseMesencephalic serotonin content
Study
mousen: not reported in source
Brain neurotransmission
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Studied dose
1 microgram · intracerebroventricularAs given in this study (mouse).
Source sentences
Summary
FTS pretreatment with dose of 1 microgram (icv) increased the mesencephalic serotonin content, while failed to influence the hypothalamic and striatal serotonin levels.
1 context sentence(design, population, supporting numbers)
Summary · context
The dose-related effect of Facteur Thymique Serique (FTS) on hypothalamic, mesencephalic and striatal neurotransmission were investigated after intracerebroventricular (icv) administration.
Report a problemFND-0359135001
02AnimalAnimal study (in vivo)Mechanism
In mice, FTS did not influence hypothalamic serotonin levels.
In plain wordsIn mice, FTS did not change serotonin in the hypothalamus.
Peptide
Thymulin (serum thymic factor)
Outcome
No significant changeHypothalamic serotonin levels
Study
mousen: not reported in source
Brain neurotransmission
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Studied dose
1 microgram · intracerebroventricularAs given in this study (mouse).
Source sentences
Summary
FTS pretreatment with dose of 1 microgram (icv) increased the mesencephalic serotonin content, while failed to influence the hypothalamic and striatal serotonin levels.
1 context sentence(design, population, supporting numbers)
Summary · context
The dose-related effect of Facteur Thymique Serique (FTS) on hypothalamic, mesencephalic and striatal neurotransmission were investigated after intracerebroventricular (icv) administration.
Report a problemFND-0359135002
03AnimalAnimal study (in vivo)Mechanism
In mice, FTS did not influence striatal serotonin levels.
In plain wordsIn mice, FTS did not change serotonin in the striatum.
Peptide
Thymulin (serum thymic factor)
Outcome
No significant changeStriatal serotonin levels
Study
mousen: not reported in source
Brain neurotransmission
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Studied dose
1 microgram · intracerebroventricularAs given in this study (mouse).
Source sentences
Summary
FTS pretreatment with dose of 1 microgram (icv) increased the mesencephalic serotonin content, while failed to influence the hypothalamic and striatal serotonin levels.
1 context sentence(design, population, supporting numbers)
Summary · context
The dose-related effect of Facteur Thymique Serique (FTS) on hypothalamic, mesencephalic and striatal neurotransmission were investigated after intracerebroventricular (icv) administration.
Report a problemFND-0359135003
04AnimalAnimal study (in vivo)Mechanism
In mice, FTS at 0.1 microgram decreased hypothalamic dopamine content.
In plain wordsIn mice, FTS at 0.1 microgram reduced dopamine in the hypothalamus.
Peptide
Thymulin (serum thymic factor)
Outcome
DecreaseHypothalamic dopamine content
Study
mousen: not reported in source
Brain neurotransmission
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Studied dose
0.1 microgram · intracerebroventricularAs given in this study (mouse).
Source sentences
Summary
The nonapeptide in a dose of 0.1 microgram (icv) decreased the hypothalamic, while in a dose of 1 microgram the hypothalamic and also the mesencephalic dopamine content, but did not influence the striatal dopamine level.
1 context sentence(design, population, supporting numbers)
Summary · context
The dose-related effect of Facteur Thymique Serique (FTS) on hypothalamic, mesencephalic and striatal neurotransmission were investigated after intracerebroventricular (icv) administration.
Report a problemFND-0359135004
05AnimalAnimal study (in vivo)Mechanism
In mice, FTS at 1 microgram decreased hypothalamic dopamine content.
In plain wordsIn mice, FTS at 1 microgram reduced dopamine in the hypothalamus.
Peptide
Thymulin (serum thymic factor)
Outcome
DecreaseHypothalamic dopamine content
Study
mousen: not reported in source
Brain neurotransmission
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Studied dose
1 microgram · intracerebroventricularAs given in this study (mouse).
Source sentences
Summary
The nonapeptide in a dose of 0.1 microgram (icv) decreased the hypothalamic, while in a dose of 1 microgram the hypothalamic and also the mesencephalic dopamine content, but did not influence the striatal dopamine level.
1 context sentence(design, population, supporting numbers)
Summary · context
The dose-related effect of Facteur Thymique Serique (FTS) on hypothalamic, mesencephalic and striatal neurotransmission were investigated after intracerebroventricular (icv) administration.
Report a problemFND-0359135005
06AnimalAnimal study (in vivo)Mechanism
In mice, FTS at 1 microgram decreased mesencephalic dopamine content.
In plain wordsIn mice, FTS at 1 microgram reduced dopamine in the midbrain.
Peptide
Thymulin (serum thymic factor)
Outcome
DecreaseMesencephalic dopamine content
Study
mousen: not reported in source
Brain neurotransmission
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Studied dose
1 microgram · intracerebroventricularAs given in this study (mouse).
Source sentences
Summary
The nonapeptide in a dose of 0.1 microgram (icv) decreased the hypothalamic, while in a dose of 1 microgram the hypothalamic and also the mesencephalic dopamine content, but did not influence the striatal dopamine level.
1 context sentence(design, population, supporting numbers)
Summary · context
The dose-related effect of Facteur Thymique Serique (FTS) on hypothalamic, mesencephalic and striatal neurotransmission were investigated after intracerebroventricular (icv) administration.
Report a problemFND-0359135006
07AnimalAnimal study (in vivo)Mechanism
In mice, FTS did not influence striatal dopamine levels.
In plain wordsIn mice, FTS did not change dopamine in the striatum.
Peptide
Thymulin (serum thymic factor)
Outcome
No significant changeStriatal dopamine level
Study
mousen: not reported in source
Brain neurotransmission
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Studied dose
Dose not stated · intracerebroventricularAs given in this study (mouse).
Source sentences
Summary
The nonapeptide in a dose of 0.1 microgram (icv) decreased the hypothalamic, while in a dose of 1 microgram the hypothalamic and also the mesencephalic dopamine content, but did not influence the striatal dopamine level.
1 context sentence(design, population, supporting numbers)
Summary · context
The dose-related effect of Facteur Thymique Serique (FTS) on hypothalamic, mesencephalic and striatal neurotransmission were investigated after intracerebroventricular (icv) administration.
Report a problemFND-0359135007
08AnimalAnimal study (in vivo)Mechanism
In mice, FTS significantly decreased hypothalamic noradrenaline levels.
In plain wordsIn mice, FTS reduced noradrenaline in the hypothalamus.
Peptide
Thymulin (serum thymic factor)
Outcome
DecreaseHypothalamic noradrenaline level
Study
mousen: not reported in source
Brain neurotransmission
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Studied dose
1 microgram · intracerebroventricularAs given in this study (mouse).
Source sentences
Summary
FTS in a dose of 1 microgram (icv) significantly decreased the hypothalamic noradrenaline level, but did not influence the noradrenaline content of the mesencephalon and striatum.
1 context sentence(design, population, supporting numbers)
Summary · context
The dose-related effect of Facteur Thymique Serique (FTS) on hypothalamic, mesencephalic and striatal neurotransmission were investigated after intracerebroventricular (icv) administration.
Report a problemFND-0359135008
09AnimalAnimal study (in vivo)Mechanism
In mice, FTS did not influence mesencephalic noradrenaline content.
In plain wordsIn mice, FTS did not change noradrenaline in the midbrain.
Peptide
Thymulin (serum thymic factor)
Outcome
No significant changeMesencephalic noradrenaline content
Study
mousen: not reported in source
Brain neurotransmission
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Studied dose
1 microgram · intracerebroventricularAs given in this study (mouse).
Source sentences
Summary
FTS in a dose of 1 microgram (icv) significantly decreased the hypothalamic noradrenaline level, but did not influence the noradrenaline content of the mesencephalon and striatum.
1 context sentence(design, population, supporting numbers)
Summary · context
The dose-related effect of Facteur Thymique Serique (FTS) on hypothalamic, mesencephalic and striatal neurotransmission were investigated after intracerebroventricular (icv) administration.
Report a problemFND-0359135009
10AnimalAnimal study (in vivo)Mechanism
In mice, FTS did not influence striatal noradrenaline content.
In plain wordsIn mice, FTS did not change noradrenaline in the striatum.
Peptide
Thymulin (serum thymic factor)
Outcome
No significant changeStriatal noradrenaline content
Study
mousen: not reported in source
Brain neurotransmission
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Studied dose
1 microgram · intracerebroventricularAs given in this study (mouse).
Source sentences
Summary
FTS in a dose of 1 microgram (icv) significantly decreased the hypothalamic noradrenaline level, but did not influence the noradrenaline content of the mesencephalon and striatum.
1 context sentence(design, population, supporting numbers)
Summary · context
The dose-related effect of Facteur Thymique Serique (FTS) on hypothalamic, mesencephalic and striatal neurotransmission were investigated after intracerebroventricular (icv) administration.
Report a problemFND-0359135010

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
21 Oct 2026, 15:58 UTC
Study results updated
Version 1
21 Oct 2026, 12:50 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

Journal Article

MeSH terms

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