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Study · Measured the body's own peptide · 1986

5 results

Responses of neurohypophysial peptides to hypertonic saline and insulin-induced hypoglycaemia in man.

Nussey SS, Ang VT, Finer N, Jenkins JS

Clinical endocrinology1 Jan 1986Cited by 22 (Europe PMC)

PMID3519006 (opens in a new tab)DOI10.1111/j.1365-2265.1986.tb03259.x (opens in a new tab)PepBankPUB-03519006
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Natural levels measured5

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    Two subjects showed a rise in plasma oxytocin when retested with 0.19 U/kg soluble insulin.

    In plain wordsTwo people showed a rise in the body's own oxytocin when tested again with a higher insulin dose.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin rise on retest with 0.19 U/kg insulin
    Study

    n = 2

    Outcome group
    Pituitary hormones · Endocrine and hormones

    Source sentences

    Summary
    Two subjects also showed a rise when retested with 0.19 U/kg soluble insulin.
    1 context sentence
    Summary · context
    plasma immunoreactive oxytocin was measured during hypertonic saline infusion and insulin-induced hypoglycaemia in a group of normal subjects, four patients with idiopathic diabetes insipidus and one patient with DIDMOAD syndrome

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    One highly symptomatic volunteer showed a marked rise in plasma oxytocin during insulin-induced hypoglycaemia.

    In plain wordsIn one volunteer with strong symptoms of low blood sugar, the body's own oxytocin rose markedly.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin rise in one symptomatic volunteer during hypoglycaemia
    Study

    n = 1

    Outcome group
    Pituitary hormones · Endocrine and hormones

    Source sentences

    Summary
    One highly symptomatic volunteer showed a marked rise in oxytocin.
    1 context sentence
    Summary · context
    plasma immunoreactive oxytocin was measured during hypertonic saline infusion and insulin-induced hypoglycaemia in a group of normal subjects, four patients with idiopathic diabetes insipidus and one patient with DIDMOAD syndrome

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    In normal subjects and in patients with diabetes insipidus, plasma oxytocin did not rise during hypertonic saline infusion.

    In plain wordsIn people, the body's own oxytocin level did not rise when salt water was infused.

    Peptide
    Oxytocin
    Outcome
    No significant changePlasma oxytocin during hypertonic saline infusion
    Study

    n: not reported in source

    Outcome group
    Pituitary hormones · Endocrine and hormones

    Source sentences

    Summary
    Plasma oxytocin did not rise during hypertonic saline infusion in either group of subjects.
    1 context sentence
    Summary · context
    plasma immunoreactive oxytocin was measured during hypertonic saline infusion and insulin-induced hypoglycaemia in a group of normal subjects, four patients with idiopathic diabetes insipidus and one patient with DIDMOAD syndrome

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  4. 04HumanEndogenous levelObservational studyOther

    In normal subjects, the plasma oxytocin response to insulin-induced hypoglycaemia was much more variable.

    In plain wordsIn healthy people, the body's own oxytocin response to low blood sugar was much more variable.

    Peptide
    Oxytocin
    Outcome
    MixedPlasma oxytocin response to insulin-induced hypoglycaemia in normal subjects
    Study

    n: not reported in source

    Outcome group
    Pituitary hormones · Endocrine and hormones

    Source sentences

    Summary
    The response of oxytocin to insulin-induced hypoglycaemia (0.15 U/kg soluble insulin) in normal subjects was much more variable.
    1 context sentence
    Summary · context
    plasma immunoreactive oxytocin was measured during hypertonic saline infusion and insulin-induced hypoglycaemia in a group of normal subjects, four patients with idiopathic diabetes insipidus and one patient with DIDMOAD syndrome

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  5. 05HumanEndogenous levelObservational studyOther

    In patients with diabetes insipidus, plasma oxytocin did not respond to a standard-dose insulin test.

    In plain wordsIn people with diabetes insipidus, the body's own oxytocin did not respond to an insulin test.

    Peptide
    Oxytocin
    Outcome
    No significant changeOxytocin response to insulin test in diabetes insipidus
    Study

    n: not reported in source

    Outcome group
    Pituitary hormones · Endocrine and hormones

    Source sentences

    Summary
    There was no response of oxytocin to a standard-dose insulin test in the patients with diabetes insipidus.
    1 context sentence
    Summary · context
    plasma immunoreactive oxytocin was measured during hypertonic saline infusion and insulin-induced hypoglycaemia in a group of normal subjects, four patients with idiopathic diabetes insipidus and one patient with DIDMOAD syndrome

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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