Effects of DSIP, 5-HTP and serotonin on the lymphokine system: a preliminary study.

Yehuda S, Shredny B, Kalechman Y

The International journal of neuroscience1 Apr 1987Cited by 10 (Europe PMC)

PMID3496316DOI10.3109/00207458708987403PepBankPUB-03496316

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study8

8 results from studies that gave the peptide. No result from this study comes from people.

01AnimalOther designMechanism
In a preliminary study, DSIP treatment significantly decreased IL-3 level 10 and 30 min after treatment.
In plain wordsIn a preliminary study, DSIP lowered IL-3, an immune signal, 10 and 30 minutes after treatment.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
DecreaseIL-3 level 10 and 30 min after treatment
Study
n: not reported in source
Outcome group
Immune response · Immune and inflammation
Studied dose
Dose not stated
Source sentences
Summary
DSIP treatment after 10 and 30 min caused a significant decrease in IL-3 and CSF levels, response to CSF-1 and CSF-GM, IL-2 level, number of IL-2 receptors and in cell proliferation.
1 context sentence(design, population, supporting numbers)
Summary · context
Short term effects of the sleep promoting substances DSIP, 5-HTP and 5-HT on the function of the lymphokine system were studied 10 and 30 min after treatment.
Report a problemFND-0349631601
02AnimalOther designMechanism
In a preliminary study, DSIP treatment significantly decreased CSF levels 10 and 30 min after treatment.
In plain wordsIn a preliminary study, DSIP lowered colony-stimulating factor (CSF) levels 10 and 30 minutes after treatment.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
DecreaseCSF level 10 and 30 min after treatment
Study
n: not reported in source
Outcome group
Immune response · Immune and inflammation
Studied dose
Dose not stated
Source sentences
Summary
DSIP treatment after 10 and 30 min caused a significant decrease in IL-3 and CSF levels, response to CSF-1 and CSF-GM, IL-2 level, number of IL-2 receptors and in cell proliferation.
1 context sentence(design, population, supporting numbers)
Summary · context
Short term effects of the sleep promoting substances DSIP, 5-HTP and 5-HT on the function of the lymphokine system were studied 10 and 30 min after treatment.
Report a problemFND-0349631602
03AnimalOther designMechanism
In a preliminary study, DSIP treatment significantly decreased the response to CSF-1 10 and 30 min after treatment.
In plain wordsIn a preliminary study, DSIP lowered the response to CSF-1, an immune growth signal, 10 and 30 minutes after treatment.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
DecreaseResponse to CSF-1
Study
n: not reported in source
Outcome group
Immune response · Immune and inflammation
Studied dose
Dose not stated
Source sentences
Summary
DSIP treatment after 10 and 30 min caused a significant decrease in IL-3 and CSF levels, response to CSF-1 and CSF-GM, IL-2 level, number of IL-2 receptors and in cell proliferation.
1 context sentence(design, population, supporting numbers)
Summary · context
Short term effects of the sleep promoting substances DSIP, 5-HTP and 5-HT on the function of the lymphokine system were studied 10 and 30 min after treatment.
Report a problemFND-0349631603
04AnimalOther designMechanism
In a preliminary study, DSIP treatment significantly decreased the response to CSF-GM 10 and 30 min after treatment.
In plain wordsIn a preliminary study, DSIP lowered the response to CSF-GM, an immune growth signal, 10 and 30 minutes after treatment.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
DecreaseResponse to CSF-GM
Study
n: not reported in source
Outcome group
Immune response · Immune and inflammation
Studied dose
Dose not stated
Source sentences
Summary
DSIP treatment after 10 and 30 min caused a significant decrease in IL-3 and CSF levels, response to CSF-1 and CSF-GM, IL-2 level, number of IL-2 receptors and in cell proliferation.
1 context sentence(design, population, supporting numbers)
Summary · context
Short term effects of the sleep promoting substances DSIP, 5-HTP and 5-HT on the function of the lymphokine system were studied 10 and 30 min after treatment.
Report a problemFND-0349631604
05AnimalOther designMechanism
In a preliminary study, DSIP treatment significantly decreased IL-2 level 10 and 30 min after treatment.
In plain wordsIn a preliminary study, DSIP lowered IL-2, an immune signal, 10 and 30 minutes after treatment.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
DecreaseIL-2 level
Study
n: not reported in source
Outcome group
Immune response · Immune and inflammation
Studied dose
Dose not stated
Source sentences
Summary
DSIP treatment after 10 and 30 min caused a significant decrease in IL-3 and CSF levels, response to CSF-1 and CSF-GM, IL-2 level, number of IL-2 receptors and in cell proliferation.
1 context sentence(design, population, supporting numbers)
Summary · context
Short term effects of the sleep promoting substances DSIP, 5-HTP and 5-HT on the function of the lymphokine system were studied 10 and 30 min after treatment.
Report a problemFND-0349631605
06AnimalOther designMechanism
In a preliminary study, DSIP treatment significantly decreased the number of IL-2 receptors 10 and 30 min after treatment.
In plain wordsIn a preliminary study, DSIP lowered the number of IL-2 receptors 10 and 30 minutes after treatment.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
DecreaseNumber of IL-2 receptors
Study
n: not reported in source
Outcome group
Immune response · Immune and inflammation
Studied dose
Dose not stated
Source sentences
Summary
DSIP treatment after 10 and 30 min caused a significant decrease in IL-3 and CSF levels, response to CSF-1 and CSF-GM, IL-2 level, number of IL-2 receptors and in cell proliferation.
1 context sentence(design, population, supporting numbers)
Summary · context
Short term effects of the sleep promoting substances DSIP, 5-HTP and 5-HT on the function of the lymphokine system were studied 10 and 30 min after treatment.
Report a problemFND-0349631606
07AnimalOther designMechanism
In a preliminary study, DSIP treatment significantly decreased cell proliferation 10 and 30 min after treatment.
In plain wordsIn a preliminary study, DSIP lowered cell growth 10 and 30 minutes after treatment.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
DecreaseCell proliferation
Study
n: not reported in source
Outcome group
Immune response · Immune and inflammation
Studied dose
Dose not stated
Source sentences
Summary
DSIP treatment after 10 and 30 min caused a significant decrease in IL-3 and CSF levels, response to CSF-1 and CSF-GM, IL-2 level, number of IL-2 receptors and in cell proliferation.
1 context sentence(design, population, supporting numbers)
Summary · context
Short term effects of the sleep promoting substances DSIP, 5-HTP and 5-HT on the function of the lymphokine system were studied 10 and 30 min after treatment.
Report a problemFND-0349631607
08AnimalOther designMechanism
In a preliminary study, DSIP first decreased IL-1 level after 10 min, followed by an increase after 30 min.
In plain wordsIn a preliminary study, DSIP first lowered IL-1, an immune signal, at 10 minutes and then raised it at 30 minutes.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
MixedIL-1 level
Study
n: not reported in source
Outcome group
Immune response · Immune and inflammation
Studied dose
Dose not stated
Source sentences
Summary
DSIP initially induced (after 10 min) a decrease to be followed (after 30 min) by an increase in IL-1 level.
Report a problemFND-0349631608

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
9 Oct 2026, 18:17 UTC
Study results updated
Version 1
9 Oct 2026, 03:04 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

MeSH terms

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