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Study · Animal study (in vivo) · mouse · 1987

2 results

Enhanced frequency of mitogen-responsive T cell precursors in old mice injected with thymosin alpha 1.

Frasca D, Adorini L, Doria G

European journal of immunology1 May 1987Cited by 34 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In old mice, a single injection of thymosin alpha‑1 increased the splenic frequency of mitogen-responsive T lymphocytes.

    In plain wordsIn old mice, thymosin alpha‑1 increased the number of spleen T cells that respond to a mitogen.

    Outcome
    IncreaseFrequency of mitogen-responsive T cell precursors in old mice
    Study

    mousen: not reported in source

    Young (3-month) and old (19-20-month) mice
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · intraperitoneal · single injectionAs given in this study (mouse).

    Source sentences

    Summary
    Injection of thymosin alpha 1 or of its N14 fragment increases the frequency of responsive T lymphocytes in old, but not in young mice
    1 context sentence
    Summary · context
    Young (3-month-old) or old (19-20-month-old) mice received a single i.p. injection of thymosin alpha 1
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In young mice, a single injection of thymosin alpha‑1 did not increase the frequency of responsive T lymphocytes.

    In plain wordsIn young mice, thymosin alpha‑1 did not increase the number of responsive spleen T cells.

    Outcome
    No significant changeFrequency of mitogen-responsive T cell precursors in young mice
    Study

    mousen: not reported in source

    Young (3-month) and old (19-20-month) mice
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · intraperitoneal · single injectionAs given in this study (mouse).

    Source sentences

    Summary
    Injection of thymosin alpha 1 or of its N14 fragment increases the frequency of responsive T lymphocytes in old, but not in young mice
    1 context sentence
    Summary · context
    Young (3-month-old) or old (19-20-month-old) mice received a single i.p. injection of thymosin alpha 1

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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