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Study · Animal study (in vivo) · rabbit · 1988

4 results

[The role of delta sleep-inducing peptide in the electric stability of the heart].

Zviaginsteva MA

Kardiologiia1 Mar 1988

PMID3379896 (opens in a new tab)PepBankPUB-03379896
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rabbits, delta-sleep peptide at 60 nM/kg raised the threshold for ventricular fibrillation.

    In plain wordsIn rabbits, DSIP made the heart harder to push into ventricular fibrillation by raising its threshold.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseVentricular fibrillation threshold
    Study

    rabbitn: not reported in source

    Outcome group
    Heart function · Cardiovascular
    Studied dose
    60 nM/kgAs given in this study (rabbit).

    Measurements

    Dose
    60 nM/kg
    delta-sleep peptide

    Source sentences

    Summary
    The delta-sleep peptide (60 nM/kg) was shown to increase electric stability of the heart by elevating the thresholds of ventricular fibrillation and its precursors (ventricular extrasystoles and paroxysmal ventricular tachysystoles).
    1 context sentence
    Summary · context
    An experimental study in 38 rabbits explored the effect of delta-sleep peptide and its deficiency on thresholds of ventricular fibrillation or its precursors.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rabbits, delta-sleep peptide at 60 nM/kg raised the threshold for ventricular extrasystoles.

    In plain wordsIn rabbits, DSIP raised the threshold at which extra heartbeats from the ventricles appeared.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseVentricular extrasystole threshold
    Study

    rabbitn: not reported in source

    Outcome group
    Heart function · Cardiovascular
    Studied dose
    60 nM/kgAs given in this study (rabbit).

    Measurements

    Dose
    60 nM/kg
    delta-sleep peptide

    Source sentences

    Summary
    The delta-sleep peptide (60 nM/kg) was shown to increase electric stability of the heart by elevating the thresholds of ventricular fibrillation and its precursors (ventricular extrasystoles and paroxysmal ventricular tachysystoles).
    1 context sentence
    Summary · context
    An experimental study in 38 rabbits explored the effect of delta-sleep peptide and its deficiency on thresholds of ventricular fibrillation or its precursors.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rabbits, delta-sleep peptide at 60 nM/kg raised the threshold for paroxysmal ventricular tachysystoles.

    In plain wordsIn rabbits, DSIP raised the threshold at which bursts of fast ventricular beats appeared.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseParoxysmal ventricular tachysystole threshold
    Study

    rabbitn: not reported in source

    Outcome group
    Heart function · Cardiovascular
    Studied dose
    60 nM/kgAs given in this study (rabbit).

    Measurements

    Dose
    60 nM/kg
    delta-sleep peptide

    Source sentences

    Summary
    The delta-sleep peptide (60 nM/kg) was shown to increase electric stability of the heart by elevating the thresholds of ventricular fibrillation and its precursors (ventricular extrasystoles and paroxysmal ventricular tachysystoles).
    1 context sentence
    Summary · context
    An experimental study in 38 rabbits explored the effect of delta-sleep peptide and its deficiency on thresholds of ventricular fibrillation or its precursors.

Studies that did not test the peptide alone1

In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Delta sleep-inducing peptide (DSIP).

  1. 04AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Efficacy outcome

    In rabbits, systemic deficiency of delta-sleep peptide, made with antiserum, was associated with lower ventricular arrhythmia thresholds.

    In plain wordsIn rabbits, removing the body's own DSIP with antiserum was linked to lower thresholds for ventricular rhythm problems.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseVentricular arrhythmia thresholds after antiserum against DSIP
    Study

    rabbitn: not reported in source

    Outcome group
    Heart function · Cardiovascular

    Source sentences

    Summary
    Systemic deficiency of this peptide (the administration of antiserum T = 1:2000--1:3000, at 1:60 dilution) was, on the contrary, associated with lower ventricular arrhythmia thresholds.
    1 context sentence
    Summary · context
    An experimental study in 38 rabbits explored the effect of delta-sleep peptide and its deficiency on thresholds of ventricular fibrillation or its precursors.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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