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Study · Measured the body's own peptide · 1988

2 results

Purification and characterization of DSIP-like material from ovine pineal glands: possible peptide-protein interaction.

Noteborn HP, Graf MV, Ernst A, Schoenenberger GA, Weusten JA, Ebels I, Salemink CA

Journal of pineal research1 Jan 1988Cited by 3 (Europe PMC)

PMID3367267 (opens in a new tab)DOI10.1111/j.1600-079x.1988.tb00779.x (opens in a new tab)PepBankPUB-03367267
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueMechanism

    In ovine pineal gland extracts, radioimmunoassay found considerable DSIP-like immunoreactivity in small and large molecular forms.

    In plain wordsIn sheep pineal gland extracts, the body's own DSIP-like material was found in small and large forms.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-like immunoreactivity in ovine pineal
    Study

    sheepn: not reported in source

    Ovine pineal gland extracts
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Radioimmunoassay (RIA) for DSIP-like fragments of the fractions revealed considerable amounts of pineal DSIP-like immunoreactivity (DSIP-LI) apparently existing in small as well as large molecular forms.
    1 context sentence
    Summary · context
    In order to demonstrate the natural occurrence of DSIP-like material associated with high Mr proteins in the ovine pineal, organs were water-extracted and fractionated by ultrafiltration and gel filtration.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelEx vivo tissueMechanism

    In ovine pineal gland extracts, the free DSIP-like form coeluted with synthetic DSIP nonapeptide on HPLC.

    In plain wordsIn sheep pineal gland extracts, the free natural DSIP-like material behaved like synthetic DSIP in a lab separation test.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableFree DSIP-like form compared with synthetic DSIP
    Study

    sheepn: not reported in source

    Ovine pineal gland extracts
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Acidification of large DSIP-LI forms resulted in the elution from Sephadex G-50 of Mr less than or equal to 1,000 DSIP-like material. This free DSIP-LI form coeluted with the synthetic DSIP nonapeptide from microBondapak C18 on high-performance liquid chromatography.
    1 context sentence
    Summary · context
    In order to demonstrate the natural occurrence of DSIP-like material associated with high Mr proteins in the ovine pineal, organs were water-extracted and fractionated by ultrafiltration and gel filtration.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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