Biophysical characteristics of oxytocin secretory granules isolated from ovine corpora lutea.

Rice GE

The Journal of endocrinology1 Feb 1988Cited by 2 (Europe PMC)

PMID3351422DOI10.1677/joe.0.1160267PepBankPUB-03351422

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone6

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

01LabNot a test of Oxytocin aloneEx vivo tissueOther
Oxytocin-containing secretory granules isolated from ovine corpora lutea had an isopycnic sedimentation density of 1.03 g/ml.
In plain wordsIn lab tests, oxytocin-containing granules from sheep ovaries had a density of 1.03 g/ml.
Peptide
Oxytocin
Outcome
Not applicableIsopycnic sedimentation density of luteal oxytocin granules
Study
Sheepn: not reported in source
Secretory granules isolated from ovine corpora lutea
Outcome group
Peptide structure and chemistry · Reproductive and sexual health
Measurements
Isopycnic sedimentation density
1.03 g/ml
ovine luteal granules
Source sentences
Summary
The isopynic sedimentation density (1.03 +/- 0.003 g/ml) and sedimentation coefficient (1670 S, 0.32 mol sucrose/l, 4 degrees C) of these granules have been estimated.
1 context sentence(design, population, supporting numbers)
Summary · context
Luteal oxytocin-containing secretory granules have been isolated and characterized in terms of their physicochemical parameters.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-0335142201
02LabNot a test of Oxytocin aloneEx vivo tissueOther
Oxytocin-containing secretory granules isolated from ovine corpora lutea had a sedimentation coefficient of 1670 S.
In plain wordsIn lab tests, oxytocin-containing granules from sheep ovaries had a sedimentation coefficient of 1670 S.
Peptide
Oxytocin
Outcome
Not applicableSedimentation coefficient of luteal oxytocin granules
Study
Sheepn: not reported in source
Secretory granules isolated from ovine corpora lutea
Outcome group
Peptide structure and chemistry · Reproductive and sexual health
Measurements
Sedimentation coefficient
1670 S
0.32 mol sucrose/l, 4 degrees C
Source sentences
Summary
The isopynic sedimentation density (1.03 +/- 0.003 g/ml) and sedimentation coefficient (1670 S, 0.32 mol sucrose/l, 4 degrees C) of these granules have been estimated.
1 context sentence(design, population, supporting numbers)
Summary · context
Luteal oxytocin-containing secretory granules have been isolated and characterized in terms of their physicochemical parameters.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-0335142202
03LabNot a test of Oxytocin aloneEx vivo tissueOther
The calculated average diameter of oxytocin-containing luteal granules was 258 nm.
In plain wordsIn lab tests, oxytocin-containing granules from sheep ovaries had an average diameter of 258 nm.
Peptide
Oxytocin
Outcome
Not applicableAverage vesicle diameter of luteal oxytocin granules
Study
Sheepn: not reported in source
Secretory granules isolated from ovine corpora lutea
Outcome group
Peptide structure and chemistry · Reproductive and sexual health
Measurements
Average vesicle diameter
258 nm
ovine luteal granules
Source sentences
Summary
Based upon these estimates, the average vesicle diameter (258 +/- 17 nm) and vesicle weight (9.92 +/- 0.67 fg/vesicle) were calculated.
1 context sentence(design, population, supporting numbers)
Summary · context
Luteal oxytocin-containing secretory granules have been isolated and characterized in terms of their physicochemical parameters.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-0335142203
04LabNot a test of Oxytocin aloneEx vivo tissueOther
The calculated vesicle weight of oxytocin-containing luteal granules was 9.92 fg per vesicle.
In plain wordsIn lab tests, oxytocin-containing granules from sheep ovaries weighed 9.92 fg each.
Peptide
Oxytocin
Outcome
Not applicableVesicle weight of luteal oxytocin granules
Study
Sheepn: not reported in source
Secretory granules isolated from ovine corpora lutea
Outcome group
Peptide structure and chemistry · Reproductive and sexual health
Measurements
Vesicle weight
9.92 fg/vesicle
ovine luteal granules
Source sentences
Summary
Based upon these estimates, the average vesicle diameter (258 +/- 17 nm) and vesicle weight (9.92 +/- 0.67 fg/vesicle) were calculated.
1 context sentence(design, population, supporting numbers)
Summary · context
Luteal oxytocin-containing secretory granules have been isolated and characterized in terms of their physicochemical parameters.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-0335142204
05LabNot a test of Oxytocin aloneEx vivo tissueOther
The exchangeable water content of oxytocin-containing luteal granules was 58.2%.
In plain wordsIn lab tests, oxytocin-containing granules from sheep ovaries had an exchangeable water content of 58.2%.
Peptide
Oxytocin
Outcome
Not applicableExchangeable water content of luteal oxytocin granules
Study
Sheepn: not reported in source
Secretory granules isolated from ovine corpora lutea
Outcome group
Peptide structure and chemistry · Reproductive and sexual health
Measurements
Exchangeable water content
58.2%
ovine luteal granules
Source sentences
Summary
The exchangeable water content (58.2%) of these granules was determined using density gradients prepared with deuterium oxide.
1 context sentence(design, population, supporting numbers)
Summary · context
Luteal oxytocin-containing secretory granules have been isolated and characterized in terms of their physicochemical parameters.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-0335142205
06LabNot a test of Oxytocin aloneEx vivo tissueOther
Luteal oxytocin-containing granules were 1.3 times greater in diameter than neurohypophysial granules, with otherwise similar physicochemical characteristics.
In plain wordsIn lab tests, sheep ovary oxytocin granules were 1.3 times wider than pituitary granules but otherwise similar.
Peptide
Oxytocin
Outcome
Not applicableGranule diameter, luteal versus neurohypophysial granules
Study
Sheepn: not reported in source
Secretory granules isolated from ovine corpora lutea
Comparator
Neurohypophysial peptide-containing granules
Outcome group
Peptide structure and chemistry · Reproductive and sexual health
Measurements
Diameter ratio
1.3 times
luteal versus neurohypophysial granules
Source sentences
Summary
Luteal oxytocin-containing granules displayed similar physicochemical characteristics to those reported for neurohypophysial peptide-containing granules, with the exception of particle size. Luteal granules were 1.3 times greater in diameter than neurohypophysial granules.
1 context sentence(design, population, supporting numbers)
Summary · context
Luteal oxytocin-containing secretory granules have been isolated and characterized in terms of their physicochemical parameters.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-0335142206

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
11 Oct 2026, 20:03 UTC
Study results updated
Version 1
9 Oct 2026, 02:52 UTC
First added · source update from Europe PMC

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