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Study · In vitro (cells) · mouse · 1988

2 results

Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures.

Takahashi N, Yamana H, Yoshiki S, Roodman GD, Mundy GR, Jones SJ, Boyde A, Suda T

Endocrinology1 Apr 1988Cited by 502 (Europe PMC)

PMID3345718 (opens in a new tab)DOI10.1210/endo-122-4-1373 (opens in a new tab)PepBankPUB-03345718
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In mouse marrow cultures, salmon calcitonin markedly inhibited hormone-induced TRACP-positive multinucleated cell formation.

    In plain wordsIn cells from mouse marrow, salmon calcitonin inhibited hormone-induced osteoclast-like cell formation.

    Peptide
    Calcitonin-salmon
    Outcome
    DecreaseTRACP-positive multinucleated cell formation
    Study

    mousen: not reported in source

    Mouse bone marrow cultures
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Salmon calcitonin markedly inhibited the formation of TRACP-positive multinucleated cells but not TRACP-positive mononuclear cell clusters induced by 1 alpha,25-(OH)2D3 or PTH.
    1 context sentence
    Summary · context
    We developed a mouse bone marrow culture system to examine the process of osteoclast-like multinucleated cell formation from its progenitors.
  2. 02LabIn vitro (cells)Activity measurement

    In mouse marrow cultures, salmon calcitonin did not inhibit hormone-induced TRACP-positive mononuclear cell clusters.

    In plain wordsIn cells from mouse marrow, salmon calcitonin did not inhibit hormone-induced mononuclear cell clusters.

    Peptide
    Calcitonin-salmon
    Outcome
    Direction not reportedTRACP-positive mononuclear cell clusters
    Study

    mousen: not reported in source

    Mouse bone marrow cultures
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Salmon calcitonin markedly inhibited the formation of TRACP-positive multinucleated cells but not TRACP-positive mononuclear cell clusters induced by 1 alpha,25-(OH)2D3 or PTH.
    1 context sentence
    Summary · context
    We developed a mouse bone marrow culture system to examine the process of osteoclast-like multinucleated cell formation from its progenitors.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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