In postoperative patients receiving lidocaine, added subarachnoid salmon calcitonin significantly reduced pain versus lidocaine plus saline.
In plain wordsIn postoperative patients, salmon calcitonin plus lidocaine reduced pain more than lidocaine plus saline.
- Peptide
- Calcitonin-salmon
- Outcome
- DecreasePostoperative pain
- Study
n = 60
- Comparator
- Lidocaine plus saline
- Outcome group
- Pain · Nervous system and cognition
- Studied dose
- 100 IU · subarachnoidAs given in this study (human).
Source sentences
In all instances, the sCT-treated patients had significantly less postoperative pain.
2 context sentences(design, population, supporting numbers)
A randomized double-blind study tested the analgesic effects of subarachnoid administration of salmon calcitonin (sCT) in acute postoperative pain.
Sixty patients were grouped according to type of surgery (intraabdominal, extraabdominal, and lower extremities), subdivided into those given subarachnoid lidocaine 1 mg/kg plus sCT (100 IU) or lidocaine plus saline.