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Study · Not a test of the peptide alone · 1988

4 results

Improved ELISA to measure thymosin alpha 1: comparison of whole and absorbed antisera.

Wada S, Naylor PH, Naylor CW, Goldstein AL

International journal of immunopharmacology1 Jan 1988Cited by 12 (Europe PMC)

PMID3235237 (opens in a new tab)DOI10.1016/0192-0561(88)90002-1 (opens in a new tab)PepBankPUB-03235237
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

  1. 01HumanNot a test of Thymosin alpha-1 aloneObservational studyOther

    In eight human cord serum samples, the ELISA with whole antiserum gave a mean thymosin alpha‑1 level similar to radioimmunoassay.

    In plain wordsIn eight cord blood samples, the ELISA with whole antiserum and the older radioimmunoassay gave similar thymosin alpha‑1 levels.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableT alpha 1 level in cord sera with whole antiserum, ELISA and RIA
    Study

    n = 8

    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    T alpha 1 level, ELISA
    2480 pg/ml
    whole antiserum, cord sera
    T alpha 1 level, RIA
    2360 pg/ml
    whole antiserum, cord sera

    Source sentences

    Summary
    Using the whole antiserum, the average T alpha 1 level was 2480 +/- 1110 (mean +/- S.D.) pg/ml by ELISA and 2360 +/- 870 pg/ml by radioimmunoassay (RIA) in eight different samples of human cord sera.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

  2. 02HumanNot a test of Thymosin alpha-1 aloneObservational studyOther

    With the absorbed N-specific antiserum, the mean thymosin alpha‑1 level in human cord sera was similar by ELISA and radioimmunoassay.

    In plain wordsWith the absorbed antiserum, the ELISA and the radioimmunoassay again gave similar thymosin alpha‑1 levels in cord blood.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableT alpha 1 level in cord sera with absorbed antiserum, ELISA and RIA
    Study

    n = 8

    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    T alpha 1 level, ELISA
    11.8 pg/ml
    absorbed antiserum, cord sera
    T alpha 1 level, RIA
    10.6 pg/ml
    absorbed antiserum, cord sera

    Source sentences

    Summary
    Using the N-specific absorbed antiserum the mean T alpha 1 level was 11,800 +/- 4800 pg/ml by ELISA and 10,600 +/- 5200 pg/ml by RIA.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

  3. 03HumanNot a test of Thymosin alpha-1 aloneObservational studyOther

    Recovery of exogenously added thymosin alpha‑1 was complete with both the whole and the absorbed antiserum.

    In plain wordsThe assay recovered all of the thymosin alpha‑1 that was added, with both antisera.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableRecovery of exogenously added T alpha 1
    Study

    n: not reported in source

    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Recovery
    109%
    whole antiserum
    Recovery
    108%
    absorbed antiserum

    Source sentences

    Summary
    Recoveries of exogenously added T alpha 1 are complete (109 +/- 25% for whole and 108 +/- 15% for absorbed antisera).

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

  4. 04HumanNot a test of Thymosin alpha-1 aloneObservational studyOther

    Thymosin alpha‑1 values measured with the absorbed antiserum were significantly higher, by 3-5 times, than values measured with the whole antiserum.

    In plain wordsThe absorbed antiserum gave thymosin alpha‑1 values 3 to 5 times higher than the whole antiserum, with higher sensitivity and specificity.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseT alpha 1 values with absorbed versus whole antiserum
    Study

    n: not reported in source

    Comparator
    Whole antiserum
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Fold difference
    3 to 5x
    absorbed versus whole antiserum

    Source sentences

    Summary
    The absorbed antiserum has an increased affinity for the amino acid terminal region of T alpha 1 and the T alpha 1 values by use of absorbed antisera are significantly higher (3-5 x) than those measured using the whole antisera.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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