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Study · Other design · 1988

6 results

Inhibitory influence of oxytocin infusion on contingent negative variation and some memory tasks in normal men.

Geenen V, Adam F, Baro V, Mantanus H, Ansseau M, Timsit-Berthier M, Legros JJ

Psychoneuroendocrinology1 Jan 1988Cited by 20 (Europe PMC)

PMID3205904 (opens in a new tab)DOI10.1016/0306-4530(88)90043-1 (opens in a new tab)PepBankPUB-03205904
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. 6 results from people.

  1. 01HumanOther designEfficacy outcome

    In normal men, intravenous oxytocin infusion significantly decreased contingent negative variation amplitude in vertex derivations.

    In plain wordsIn men, oxytocin given into a vein lowered a brain-wave signal linked to attention.

    Peptide
    Oxytocin
    Outcome
    DecreaseContingent negative variation amplitude
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intravenous infusionAs given in this study (Human).

    Source sentences

    Summary
    OT infusion induced a significant decrease of CNV amplitude
    1 context sentence
    Summary · context
    A double-blind study combining electrophysiological and psychometrical approaches was carried out to investigate the central effects of an intravenous oxytocin (OT) infusion in normal men.
  2. 02HumanOther designEfficacy outcome

    In normal men, intravenous oxytocin infusion increased post-imperative positive potentials in vertex derivations.

    In plain wordsIn men, oxytocin given into a vein raised a later brain-wave signal.

    Peptide
    Oxytocin
    Outcome
    IncreasePost-imperative positive potentials
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intravenous infusionAs given in this study (Human).

    Source sentences

    Summary
    an increase of post-imperative positive potentials in vertex derivations.
    1 context sentence
    Summary · context
    A double-blind study combining electrophysiological and psychometrical approaches was carried out to investigate the central effects of an intravenous oxytocin (OT) infusion in normal men.
  3. 03HumanOther designEfficacy outcome

    In normal men, a similar effect of oxytocin on brain potentials was still seen one week after treatment in frontal derivations.

    In plain wordsIn men, the brain-wave change after oxytocin was still present one week later.

    Peptide
    Oxytocin
    Outcome
    DecreaseCNV effect one week after treatment (frontal derivations)
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intravenous infusionAs given in this study (Human).

    Source sentences

    Summary
    A similar effect was still evidenced one week after treatment in frontal derivations, suggesting a long time effect of OT on human brain.
    1 context sentence
    Summary · context
    A double-blind study combining electrophysiological and psychometrical approaches was carried out to investigate the central effects of an intravenous oxytocin (OT) infusion in normal men.
  4. 04HumanOther designEfficacy outcome

    In normal men, intravenous oxytocin had no significant influence on mood tests.

    In plain wordsIn men, oxytocin given into a vein did not change mood test results.

    Peptide
    Oxytocin
    Outcome
    No significant changeMood tests
    Study

    n: not reported in source

    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated · intravenous infusionAs given in this study (Human).

    Source sentences

    Summary
    No significant influence of OT on mood or vigilance tests was apparent
    1 context sentence
    Summary · context
    A double-blind study combining electrophysiological and psychometrical approaches was carried out to investigate the central effects of an intravenous oxytocin (OT) infusion in normal men.
  5. 05HumanOther designEfficacy outcome

    In normal men, intravenous oxytocin had no significant influence on vigilance tests.

    In plain wordsIn men, oxytocin given into a vein did not change vigilance test results.

    Peptide
    Oxytocin
    Outcome
    No significant changeVigilance tests
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intravenous infusionAs given in this study (Human).

    Source sentences

    Summary
    No significant influence of OT on mood or vigilance tests was apparent
    1 context sentence
    Summary · context
    A double-blind study combining electrophysiological and psychometrical approaches was carried out to investigate the central effects of an intravenous oxytocin (OT) infusion in normal men.
  6. 06HumanOther designEfficacy outcome

    In normal men, only one item of a memory test showed a significant impairment of some performances after intravenous oxytocin.

    In plain wordsIn men, oxytocin given into a vein lowered performance on only one item of a memory test.

    Peptide
    Oxytocin
    Outcome
    DecreaseMemory test performance
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intravenous infusionAs given in this study (Human).

    Source sentences

    Summary
    only one item of a memory test revealed a significant impairment of some mnesic performances.
    1 context sentence
    Summary · context
    A double-blind study combining electrophysiological and psychometrical approaches was carried out to investigate the central effects of an intravenous oxytocin (OT) infusion in normal men.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

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