In water snake plasma protein binding assays, enclomiphene citrate displaced labeled estradiol by 67.8%.
In plain wordsIn lab tests with water snake plasma protein, enclomiphene displaced labeled estradiol.
- Peptide
- Enclomiphene
- Outcome
- Not applicableDisplacement of labeled estradiol
- Study
Nerodian: not reported in source
Plasma steroid hormone binding protein- Outcome group
- Receptor activity and mechanism · Pharmacology
- Studied dose
- 100-fold excess competitor concentrationAs given in this study (Nerodia).
Measurements
- Estradiol displacement
- 67.8%
- enclomiphene citrate
Source sentences
Displacement of 3H-E by antiestrogen clomiphene derivatives and synthetic estrogen varied; enclomiphene citrate (67.8%), clomiphene citrate (42.2%), diethylstilbestrol (37.3%), and zuclomiphene citrate (15.2%).
1 context sentence(design, population, supporting numbers)
Further analysis of binding specificity for [3H]estradiol at 100-fold excess competitor concentrations revealed that dihydrotestosterone also competes; however, estrone and estriol were relatively poor competitors.