In T-cells from patients with post-irradiation abnormalities, short-term in vitro incubation with thymosin alpha‑1 enhanced the mixed lymphocyte response in 12 of 27 patients.
In plain wordsIn lab tests on T-cells taken after chest radiotherapy for lung cancer, thymosin alpha‑1 improved the cell response in 12 of 27 samples.
- Peptide
- Thymosin alpha-1
- Outcome
- IncreaseMixed lymphocyte culture response after in vitro incubation
- Study
humann = 27
T-cells from patients with non-small cell lung cancer after mediastinal irradiation- Outcome group
- Immune response · Immune and inflammation
- Studied dose
- Dose not stated
Measurements
- patients with enhanced MLR
- 12 patients
- of 27 with post-RT abnormalities
Source sentences
A short-term in vitro incubation with thymosin alpha-1 could enhance MLR of T-cells in 12 of 27 patients with post-RT abnormalities.
1 context sentence(design, population, supporting numbers)
The effects of mediastinal irradiation (RT) on the numbers and functions of purified peripheral blood T-lymphocytes from patients with locally advanced non-small cell lung cancer were evaluated.