In hamster uterine receptor preparations, enclomiphene relative binding affinity did not differ significantly between cytosolic and nuclear estrogen receptors.
In plain wordsIn lab tests, enclomiphene binding affinity did not differ significantly between cytosolic and nuclear estrogen receptors.
- Peptide
- Enclomiphene
- Outcome
- No significant changeRelative binding affinity at cytosolic versus nuclear estrogen receptors
- Study
hamstern: not reported in source
Uterine estrogen receptor preparations- Comparator
- Nuclear estrogen receptors
- Outcome group
- Receptor activity and mechanism · Pharmacology
- Studied dose
- Dose not stated
Source sentences
The RBAs of estrone, estriol and enclomiphene with cytosolic or nuclear Re were not significantly different.
1 context sentence(design, population, supporting numbers)
The biological equivalence of DES and E2 was not reflected by competition assays done with either uterine cytosolic or nuclear Re: the relative binding affinity (RBA) of DES to cytosolic Re was 46 +/- 5.3 and to nuclear Re was 380 +/- 42 compared to E2 (100).