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Study · Measured the body's own peptide · 1988

2 results

Immunocytochemical localization of vasoactive intestinal polypeptide (VIP) in the brain of the little brown bat (Myotis lucifugus).

Laemle LK, Cotter JR

Journal of neurocytology1 Feb 1988Cited by 8 (Europe PMC)

PMID3047320 (opens in a new tab)DOI10.1007/bf01735384 (opens in a new tab)PepBankPUB-03047320
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In the bat brain, the density of VIP-immunoreactive fibres and plexuses in the anterior hypothalamic area changed markedly with the physiological state of the animal.

    In plain wordsIn bats, the amount of the body's own VIP in a brain area changed with the animal's activity state, such as hibernation.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    MixedDensity of VIP-immunoreactive fibres in anterior hypothalamic area by physiological state
    Study

    little brown bat (Myotis lucifugus)n: not reported in source

    Brain tissue sections
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Our study has demonstrated marked changes in the density of VIP-immunoreactive fibres and plexuses in the anterior hypothalamic area which correspond to the physiological state of the animal.
    2 context sentences
    Summary · context
    Vasoactive intestinal polypeptide (VIP)-like immunoreactivity has been examined in the brain of the little brown bat, Myotis lucifugus, using light microscopic immunocytochemistry and the indirect antibody enzyme method of Sternberger.
    Summary · context
    Animals were sacrificed at three different and discrete levels of physiological activity: euthermic, hypothermic and hibernating.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    VIP-immunoreactive perikarya were present in several previously unreported locations of the bat brain, including paraventricular and periventricular hypothalamic nuclei and the linear raphe nucleus.

    In plain wordsIn bats, cells holding the body's own VIP were found in several brain places not reported before.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableVIP-immunoreactive perikarya in previously unreported brain locations
    Study

    little brown bat (Myotis lucifugus)n: not reported in source

    Brain tissue sections
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    In addition we have demonstrated the presence of VIP immunoreactive perikarya in a number of previously unreported locations. These include the paraventricular and periventricular hypothalamic nuclei, the linear raphe nucleus, nucleus interfascicularis, and in neurons embedded in the fibres of the d…
    2 context sentences
    Summary · context
    Vasoactive intestinal polypeptide (VIP)-like immunoreactivity has been examined in the brain of the little brown bat, Myotis lucifugus, using light microscopic immunocytochemistry and the indirect antibody enzyme method of Sternberger.
    Summary · context
    Animals were sacrificed at three different and discrete levels of physiological activity: euthermic, hypothermic and hibernating.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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