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Study · Measured the body's own peptide · 1987

4 results

Hypophysial-portal plasma levels, median eminence content, and immunohistochemical staining of corticotropin-releasing factor, arginine vasopressin, and oxytocin after pharmacological adrenalectomy.

Plotsky PM, Sawchenko PE

Endocrinology1 Apr 1987Cited by 158 (Europe PMC)

PMID3030697 (opens in a new tab)DOI10.1210/endo-120-4-1361 (opens in a new tab)PepBankPUB-03030697
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In male rats after pharmacological adrenalectomy, the body's own oxytocin immunostaining intensity stayed stable at all times examined.

    In plain wordsIn male rats, the body's own oxytocin staining in the brain did not change after adrenal hormones were blocked.

    Peptide
    Oxytocin
    Outcome
    No significant changeOxytocin immunostaining intensity after pharmacological adrenalectomy
    Study

    ratn: not reported in source

    male rats after pharmacological adrenalectomy
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    irOT staining intensity, irOT-positive cell number, median eminence irOT content, and portal plasma irOT concentration remained stable at all times examined.
    1 context sentence
    Summary · context
    Changes in immunostaining, median eminence content, and secretion into the hypophysial-portal circulation of immunoreactive CRF (irCRF), arginine vasopressin (irAVP), and oxytocin (irOT) were directly evaluated after pharmacological adrenalectomy (PHADX).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In male rats after pharmacological adrenalectomy, the number of oxytocin-positive cells stayed stable at all times examined.

    In plain wordsIn male rats, the number of cells making the body's own oxytocin did not change after adrenal hormones were blocked.

    Peptide
    Oxytocin
    Outcome
    No significant changeOxytocin-positive cell number after pharmacological adrenalectomy
    Study

    ratn: not reported in source

    male rats after pharmacological adrenalectomy
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    irOT staining intensity, irOT-positive cell number, median eminence irOT content, and portal plasma irOT concentration remained stable at all times examined.
    1 context sentence
    Summary · context
    Changes in immunostaining, median eminence content, and secretion into the hypophysial-portal circulation of immunoreactive CRF (irCRF), arginine vasopressin (irAVP), and oxytocin (irOT) were directly evaluated after pharmacological adrenalectomy (PHADX).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In male rats after pharmacological adrenalectomy, median eminence oxytocin content stayed stable at all times examined.

    In plain wordsIn male rats, the body's own oxytocin stored in a brain region did not change after adrenal hormones were blocked.

    Peptide
    Oxytocin
    Outcome
    No significant changeMedian eminence oxytocin content after pharmacological adrenalectomy
    Study

    ratn: not reported in source

    male rats after pharmacological adrenalectomy
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    irOT staining intensity, irOT-positive cell number, median eminence irOT content, and portal plasma irOT concentration remained stable at all times examined.
    1 context sentence
    Summary · context
    Changes in immunostaining, median eminence content, and secretion into the hypophysial-portal circulation of immunoreactive CRF (irCRF), arginine vasopressin (irAVP), and oxytocin (irOT) were directly evaluated after pharmacological adrenalectomy (PHADX).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Other

    In male rats after pharmacological adrenalectomy, hypophysial-portal plasma oxytocin concentration stayed stable at all times examined.

    In plain wordsIn male rats, the body's own oxytocin in the pituitary blood supply did not change after adrenal hormones were blocked.

    Peptide
    Oxytocin
    Outcome
    No significant changeHypophysial-portal plasma oxytocin after pharmacological adrenalectomy
    Study

    ratn: not reported in source

    male rats after pharmacological adrenalectomy
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    irOT staining intensity, irOT-positive cell number, median eminence irOT content, and portal plasma irOT concentration remained stable at all times examined.
    1 context sentence
    Summary · context
    Changes in immunostaining, median eminence content, and secretion into the hypophysial-portal circulation of immunoreactive CRF (irCRF), arginine vasopressin (irAVP), and oxytocin (irOT) were directly evaluated after pharmacological adrenalectomy (PHADX).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:54 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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