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Study · Ex vivo tissue · rat · 1987

2 results

Delta sleep-inducing peptide modulates the stimulation of rat pineal N-acetyltransferase activity by involving the alpha 1-adrenergic receptor.

Graf MV, Schoenenberger GA

Journal of neurochemistry1 Apr 1987Cited by 8 (Europe PMC)

PMID3029331 (opens in a new tab)DOI10.1111/j.1471-4159.1987.tb05654.x (opens in a new tab)PepBankPUB-03029331
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueMechanism

    In rat pineal in vitro, DSIP at 20-300 nM significantly enhanced N-acetyltransferase activity induced by norepinephrine.

    In plain wordsIn rat pineal tissue in a dish, DSIP boosted an enzyme response that norepinephrine had triggered.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseNorepinephrine-induced NAT activity in rat pineal
    Study

    ratn: not reported in source

    Rat pineal in vitro
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    20-300 nMAs given in this study (rat).

    Source sentences

    Summary
    DSIP in the range between 20 and 300 nM significantly enhanced NAT activity induced by 10(-6) M norepinephrine in vitro
  2. 02LabEx vivo tissueMechanism

    In rat pineal in vitro, the alpha 1-adrenergic blocker prazosin eliminated the enhancement of NAT activity.

    In plain wordsIn rat pineal tissue in a dish, a drug that blocks alpha 1 receptors removed the enhancing effect.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicablePrazosin blockade of DSIP enhancement of NAT activity
    Study

    ratn: not reported in source

    Rat pineal in vitro
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Incubation with prazosin eliminated the enhancement

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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