In conscious rats, oxytocin also lowered plasma prolactin, but it was 5-fold less potent than arginine vasopressin.
In plain wordsIn rats, oxytocin lowered blood prolactin, but it was 5-fold weaker than vasopressin.
- Peptide
- Oxytocin
- Outcome
- DecreasePlasma prolactin level
- Study
ratn: not reported in source
conscious rats- Comparator
- Arginine vasopressin
- Outcome group
- Pituitary hormones · Endocrine and hormones
- Studied dose
- Dose not stated
Source sentences
Oxytocin (OT) was also active but 5-fold less potent than AVP.
2 context sentences(design, population, supporting numbers)
Vasopressin and oxytocin reduce plasma prolactin levels of conscious rats in basal and stress conditions. Study of the characteristics of the receptor involved.
Subcutaneous administration of arginine vasopressin (AVP) to conscious rats induced a dose-dependent increase of plasma ACTH and beta-endorphin levels and decrease of plasma prolactin (PRL) levels 30 min later.