In normal volunteers, 250 micrograms cosyntropin produced no significant differences in steroid concentrations, increments, ratios, or areas above baseline between bolus injection and continuous 2-h intravenous infusion.
In plain wordsIn normal volunteers, steroid responses did not differ significantly between cosyntropin bolus injection and continuous infusion.
- Peptide
- Cosyntropin
- Outcome
- No significant changeAdrenal steroid response panel
- Study
n = 17
- Comparator
- Continuous 2-h intravenous infusion
- Outcome group
- Adrenal Function · Endocrine and hormones
Source sentences
The steroid concentrations and their increments, ratios, or areas above baseline did not differ significantly between the bolus injection and the continuous infusion.
2 context sentences(design, population, supporting numbers)
We compared the adrenal steroid responses after synthetic ACTH-(1-24) (Cosyntropin) administration given by either continuous iv infusion or bolus injection in 11 normal women and 6 normal men.
Each subject received 250 micrograms Cosyntropin as a bolus iv injection on 1 occasion and as a continuous 2-h iv infusion on another occasion, in random order.
In this study, Cosyntropin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cosyntropin.