In micropunched hypothalamic nuclei, oxytocin stimulated cAMP accumulation selectively in one or two of the paraventricular, supraoptic and lateral hypothalamic structures.
In plain wordsIn lab tests on brain tissue, oxytocin raised cAMP in one or two of the three hypothalamic areas tested.
- Peptide
- Oxytocin
- Outcome
- IncreasecAMP accumulation in hypothalamic nuclei
- Study
n: not reported in source
Micropunched hypothalamic nuclei (PVH, SON, LH)- Outcome group
- Receptor activity and mechanism · Nervous system and cognition
- Studied dose
- Dose not stated
Source sentences
Bradykinin, alpha-melanocyte-stimulating (alpha-MSH), luteinizing hormone-releasing hormone (LH-RH), oxytocin and carbamylcholine stimulated cAMP accumulation selectively in one or two of the above structures.
1 context sentence(design, population, supporting numbers)
Neuropeptides and biogenic amines known to be present in neurons or afferent terminals in the paraventricular nucleus (PVH), supraoptic nucleus (SON) and/or lateral hypothalamus (LH) were added to small areas of these structures obtained by micropuncture and cyclic adenosine monophosphate (cAMP) levels were measured.