In cells derived primarily from rabbit kidney medullary thick ascending limb, salmon calcitonin stimulated oxygenated arachidonate metabolite formation.
In plain wordsIn lab tests, salmon calcitonin stimulated formation of oxygenated arachidonate metabolites in cells derived from rabbit kidney.
- Peptide
- Calcitonin-salmon
- Outcome
- IncreaseFormation of oxygenated arachidonate metabolites
- Study
rabbitn: not reported in source
Cells derived primarily from the medullary thick ascending limb- Outcome group
- Receptor activity and mechanism · Kidney and urinary
- Studied dose
- Dose not stated
Source sentences
We report that formation of these oxygenated arachidonate metabolites is stimulated by arginine vasopressin (AVP) and salmon calcitonin (SCT).
1 context sentence(design, population, supporting numbers)
Here, in cells derived primarily from the mTALH of the outer medulla of rabbit kidney, we have identified a cytochrome P450-dependent monooxygenase system which metabolizes arachidonic acid to two biologically active oxygenated products; one of the products inhibits (Na+ + K+)ATPase and the other relaxes blood vessels.