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Study · Measured the body's own peptide · 1989

2 results

Lactation elevates vasoactive intestinal peptide messenger ribonucleic acid in rat suprachiasmatic nucleus.

Gozes I, Avidor R, Biegon A, Baldino F Jr

Endocrinology1 Jan 1989Cited by 27 (Europe PMC)

PMID2909364 (opens in a new tab)DOI10.1210/endo-124-1-181 (opens in a new tab)PepBankPUB-02909364
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In lactating rats, VIP transcripts in the suprachiasmatic nucleus showed a 2-fold increase compared with non-lactating rats.

    In plain wordsIn rats, the body's own VIP gene activity in a brain area was twice as high during lactation as without lactation.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    IncreaseVIP mRNA in suprachiasmatic nucleus, lactating versus non-lactating
    Study

    ratn: not reported in source

    Comparator
    Non-lactating rats
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Measurements

    VIP transcripts fold change
    2 fold
    lactating vs non-lactating, suprachiasmatic nucleus

    Source sentences

    Summary
    When lactating animals were compared to non-lactating animals, a 2-fold increase was observed in VIP transcripts in the suprachiasmatic nucleus.
    1 context sentence
    Summary · context
    A sensitive in situ hybridization assay employing synthetic oligodeoxynucleotide probes corresponding to specific exons of the VIP gene was used to study VIP gene expression at the neuronal level.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, VIP-encoding transcripts were detected in the ventrolateral thalamus, neocortex, pyriform cortex and hypothalamus, with a particularly high concentration in the suprachiasmatic nucleus.

    In plain wordsIn rats, the body's own VIP gene activity was found in several brain regions and was highest in the suprachiasmatic nucleus.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableRegional distribution of VIP transcripts in rat brain
    Study

    ratn: not reported in source

    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    We were able to detect VIP-encoding transcripts in various brain regions including the ventrolateral thalamus, neocortex, pyriform cortex, and hypothalamus with a particularly high concentration in the suprachiasmatic nucleus.
    1 context sentence
    Summary · context
    A sensitive in situ hybridization assay employing synthetic oligodeoxynucleotide probes corresponding to specific exons of the VIP gene was used to study VIP gene expression at the neuronal level.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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