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Study · Other design · frog · 1988

3 results

[Modulation of excitation transfer in the intracardiac ganglionic system by the opioid peptide dermorphin].

Sokolova NA, Deĭgin VI, Iarova EP

Biulleten' eksperimental'noi biologii i meditsiny1 Apr 1988

PMID2896024 (opens in a new tab)DOI10.1007/bf00841193 (opens in a new tab)PepBankPUB-02896024
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalOther designActivity measurement

    In frog intracardiac nerves, dermorphin inhibited postganglionic impulse activity.

    In plain wordsIn frog intracardiac nerves, dermorphin inhibited postganglionic impulse activity.

    Peptide
    Dermorphin
    Outcome
    DecreasePostganglionic impulse activity
    Study

    frogn: not reported in source

    Intracardiac nerves
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    10(-12)-10(-6) MAs given in this study (frog).

    Source sentences

    Summary
    It has been shown that postganglionic impulse activity recorded in the frog intracardiac nerve was inhibited by endogenous amphibian opioid peptide-dermorphin (10(-12)-10(-6) M).
  2. 02AnimalOther designActivity measurement

    In frog intracardiac sympathetic fibers, dermorphin had no influence on transitory impulse activity.

    In plain wordsIn frog intracardiac sympathetic fibers, dermorphin did not affect transitory impulse activity.

    Peptide
    Dermorphin
    Outcome
    No significant changeTransitory sympathetic impulse activity
    Study

    frogn: not reported in source

    Intracardiac nerves
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    10(-6) MAs given in this study (frog).

    Source sentences

    Summary
    Dermorphin (10(-6) M) had no influence on transitory impulse activity in the intracardiac postganglionic sympathetic fibers.

Studies that did not test the peptide alone1

In this study, Dermorphin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Dermorphin.

  1. 03AnimalNot a test of Dermorphin aloneOther designMechanism

    In frog intracardiac nerves, naloxone blocked dermorphin-induced impulse inhibition.

    In plain wordsIn frog intracardiac nerves, naloxone blocked dermorphin-induced impulse inhibition.

    Peptide
    Dermorphin
    Outcome
    Not applicableNaloxone sensitivity of impulse inhibition
    Study

    frogn: not reported in source

    Intracardiac nerves
    Outcome group
    Heart function · Cardiovascular

    Source sentences

    Summary
    The inhibition was blocked by naloxone (10(-5) M).
    1 context sentence
    Summary · context
    It has been shown that postganglionic impulse activity recorded in the frog intracardiac nerve was inhibited by endogenous amphibian opioid peptide-dermorphin (10(-12)-10(-6) M).

    In this study, Dermorphin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Dermorphin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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