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Study · Observational study · 1987

2 results

[Diagnostic use of the GRF test in the study of GH secretion].

Ramos M, Fernández A, Ferrández A, Mayayo E, Guallar A

Anales espanoles de pediatria1 Oct 1987

PMID2892455 (opens in a new tab)PepBankPUB-02892455
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanObservational studyActivity measurement

    In patients with hypopituitary dwarfism, a good response to an intravenous GRF-1-29 NH2 bolus located the GH deficiency in the hypothalamus.

    In plain wordsIn patients with hypopituitary dwarfism, a good response to a GRF test dose pointed to a hypothalamic cause of low growth hormone.

    Peptide
    Sermorelin
    Outcome
    IncreaseGH response to GRF-1-29 NH2 bolus in hypopituitary dwarfism
    Study

    n: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated · intravenous bolusAs given in this study (human).

    Source sentences

    Summary
    A good response after an intravenous bolus of GRF-1-29 NH2 in patients with hypopituitary dwarfism localities the site of the GH-deficiency in the hypothalamus (GRF deficiency).
  2. 02HumanObservational studyActivity measurement

    Some patients with hypothalamic responses after TRH did not respond after GRF.

    In plain wordsSome patients whose hypothalamus responded to TRH did not respond to GRF.

    Peptide
    Sermorelin
    Outcome
    No significant changeGH non-response to GRF in patients with hypothalamic response to TRH
    Study

    n: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Never the less some patients with hypothalamic responses after TRH don't respond after GRF.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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