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Study · Measured the body's own peptide · 1987

8 results

Thymosin alpha 1 levels in human seminal plasma and follicular fluid: implication in germ cell function.

Naz RK, Naylor PH, Goldstein AL

International journal of fertility1 Sept 1987Cited by 4 (Europe PMC)

PMID2889684 (opens in a new tab)PepBankPUB-02889684
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study8

No result from this study comes from a test of the peptide.

Natural levels measured8

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In follicular fluid from 24 follicles of 10 infertile females, thymosin alpha‑1 levels were higher than in corresponding serum.

    In plain wordsIn women with infertility, the body's own thymosin alpha‑1 was higher in follicular fluid than in blood.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseFollicular fluid versus serum thymosin alpha 1
    Study

    n = 24

    Comparator
    Corresponding serum levels
    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Measurements

    Follicular fluid thymosin alpha 1 mean
    3572.8 pg/mL
    follicular fluid
    Serum thymosin alpha 1 mean
    1666.9 pg/mL
    corresponding serum

    Source sentences

    Summary
    In follicular fluid collected from 24 follicles of 10 infertile females, T alpha 1 levels varied from 1,019 to 6,384 pg/mL (mean +/- SD, 3,572.8 +/- 1,599.7 pg/mL), which were higher when compared with the corresponding serum levels (mean +/- SD, 1,666.9 +/- 1,378.9 pg/mL).

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    Thymosin alpha‑1 levels were lower in follicular fluids with immature oocytes than in those with intermediate or mature oocytes.

    In plain wordsNatural thymosin alpha‑1 levels were lower in fluid around immature egg cells than around more mature ones.

    Peptide
    Thymosin alpha-1
    Outcome
    DecreaseFollicular fluid thymosin alpha 1 by oocyte maturity
    Study

    n = 24

    Comparator
    Follicular fluids with intermediate or mature oocytes
    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    T alpha 1 levels present in follicular fluids which had "immature" oocytes were lower when compared with follicular fluids which had "intermediate" or "mature" oocytes.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    In the seminal plasma of 19 males, thymosin alpha‑1 levels varied from 614 to 2,604 pg/mL.

    In plain wordsIn men's semen, the body's own thymosin alpha‑1 levels varied widely between men.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableSeminal plasma thymosin alpha 1 level
    Study

    n = 19

    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Measurements

    Seminal plasma thymosin alpha 1 mean
    1682.4 pg/mL
    males

    Source sentences

    Summary
    In the seminal plasma of 19 males studies, T alpha 1 levels varied from 614 to 2,604 pg/mL (mean +/- SD, 1,682.4 +/- 453.9 pg/mL).

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  4. 04HumanEndogenous levelObservational studyOther

    Seminal thymosin alpha‑1 levels correlated positively with the total number of sperm in the ejaculate (r = .18).

    In plain wordsMen with higher natural thymosin alpha‑1 levels in semen tended to have more sperm.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseThymosin alpha 1 and total sperm number
    Study

    n = 19

    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    There was a correlation between the T alpha 1 levels and the total number of sperm in the ejaculate (r = .18) and seminal volume (r = .26).

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  5. 05HumanEndogenous levelObservational studyOther

    Seminal thymosin alpha‑1 levels correlated positively with seminal volume (r = .26).

    In plain wordsMen with higher natural thymosin alpha‑1 levels in semen tended to have more semen volume.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseThymosin alpha 1 and seminal volume
    Study

    n = 19

    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    There was a correlation between the T alpha 1 levels and the total number of sperm in the ejaculate (r = .18) and seminal volume (r = .26).

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  6. 06HumanEndogenous levelObservational studyOther

    Infertile males with low thymosin alpha‑1 levels had fewer sperm.

    In plain wordsInfertile men with low natural thymosin alpha‑1 levels had fewer sperm.

    Peptide
    Thymosin alpha-1
    Outcome
    DecreaseSperm number in infertile males with low thymosin alpha 1
    Study

    n: not reported in source

    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    The infertile males, who had low levels of T alpha 1 also demonstrated fewer sperm, reduced motility, and lower semen volume.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  7. 07HumanEndogenous levelObservational studyOther

    Infertile males with low thymosin alpha‑1 levels had reduced sperm motility.

    In plain wordsInfertile men with low natural thymosin alpha‑1 levels had less sperm motility.

    Peptide
    Thymosin alpha-1
    Outcome
    DecreaseSperm motility in infertile males with low thymosin alpha 1
    Study

    n: not reported in source

    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    The infertile males, who had low levels of T alpha 1 also demonstrated fewer sperm, reduced motility, and lower semen volume.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  8. 08HumanEndogenous levelObservational studyOther

    Infertile males with low thymosin alpha‑1 levels had lower semen volume.

    In plain wordsInfertile men with low natural thymosin alpha‑1 levels had lower semen volume.

    Peptide
    Thymosin alpha-1
    Outcome
    DecreaseSemen volume in infertile males with low thymosin alpha 1
    Study

    n: not reported in source

    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    The infertile males, who had low levels of T alpha 1 also demonstrated fewer sperm, reduced motility, and lower semen volume.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

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